Minimally invasive image-guided therapy for inoperable hepatocellular carcinoma: What is the evidence today?

Insights into Imaging

Table 1 Long-term survival data from follow-up studies of HCC patients treated with RFA

Study	Patients (n)	Type of RFA	Tumor size (cm)	5-year overall survival (%)
Buscarini et al. (2001)[53]	88	perc	≤3.5	33
Lencioni et al. (2005)[54]	187	perc	Mean, 2.8	48
Tateishi et al. (2005)[55]	319 (naive)	perc	Mean, 2.6	54 (naive)
Tateishi et al. (2005)[55]	345 (pretreated)	perc	Mean, 2.6	38 (pretreated)
Raut et al. (2005)[56]	194	140 perc	Median	55
		54 open	Total 3.3
			Perc 3.0
			Open 4.0
Machi et al. (2005)[57]	84	49 perc	Mean	40
		20 lap	Total 3.2
		15 open	Perc 3.2
			Lap 3.0
			Open 3.1
Cabassa et al. (2006)[58]	59	perc	Mean, 3.1	43
Choi et al. (2006)[59]	570	perc	Mean, 2.59	58
Yan et al. (2007)[60]	266	perc	Mean, 3.9	43
Ueno et al. (2009)[61]	155	110 perc, 45	Mean, 2.0	63
Ueno et al. (2009)[61]	155	lap/open	Mean, 2.0	63

Data of studies with ≥ 50 patients included
RFA = radiofrequency ablation, perc = percutaneous, lap = laparoscopic, open = open procedure