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Table 2 Logistic regression analysis of plaque features associated with culprit plaques

From: Incremental value of enhanced plaque length for identifying intracranial atherosclerotic culprit plaques: a high-resolution magnetic resonance imaging study

 

Non-adjusted OR (95% CI)

p value

Model 1 OR (95% CI)

p value

Model 2 OR (95% CI)

p value

Plaque morphological features

      

Plaque length, (mm)

1.02 (0.99, 1.06)

0.226

1.03 (0.99, 1.07)

0.099

1.00 (0.96, 1.04)

0.926

Plaque thickness, (mm)

1.36 (0.84, 2.18)

0.209

1.56 (0.93, 2.62)

0.092

1.24 (0.66, 2.35)

0.501

Stenosis degree

      

 < 50%

1.0

 

1.0

 

1.0

 

 50–69%

1.48 (0.70, 3.14)

0.303

1.42 (0.65, 3.08)

0.381

0.62 (0.04, 9.25)

0.725

 70–99%

4.98 (2.27, 10.95)

< 0.001

4.77 (2.15, 10.60)

0.001

1.44 (0.08, 27.32)

0.807

 100%

8.67 (2.45, 30.65)

0.001

8.18 (2.28, 29.33)

0.001

0.84 (0.03, 24.96)

0.919

Plaque burden

1.07 (1.04, 1.10)

< 0.001

1.07 (1.04, 1.10)

< 0.001

1.02 (0.96, 1.08)

0.572

Remodelling index

0.29 (0.11, 0.74)

0.010

0.32 (0.12, 0.85)

0.023

0.29 (0.04, 1.91)

0.196

Remodelling mode

      

 Intermediate

1.0

 

1.0

 

1.0

 

 Positive remodelling

1.20 (0.50, 2.91)

0.680

1.32 (0.54, 3.24)

0.545

1.12 (0.41, 3.02)

0.830

 Negative remodelling

1.98 (0.86, 4.58)

0.110

2.01 (0.85, 4.76)

0.111

1.24 (0.46, 3.37)

0.674

Surface irregularity

2.90 (1.46, 5.77)

0.003

3.24 (1.61, 6.54)

0.001

1.77 (0.80, 3.94)

0.159

Plaque signal features

      

Enhanced grade

      

 Grade 0, n (%)

1.0

 

1.0

 

1.0

 

 Grade I, n (%)

1.53 (0.48, 4.85)

0.473

1.50 (0.47, 4.82)

0.492

1.31 (0.39, 4.46)

0.662

 Grade II, n (%)

14.38 (3.99, 51.78)

< 0.001

13.34 (3.64, 48.92)

< 0.001

7.00 (1.69, 28.93)

0.007

Enhanced length, (mm)

1.06 (1.02, 1.10)

0.002

1.06 (1.03, 1.10)

0.001

1.03 (0.99, 1.07)

0.129

Enhanced length, (mm)

      

 Tertile 1, (5.13 ± 2.72)

1.0

 

1.0

 

1.0

 

 Tertile 2, (13.06 ± 2.57)

1.32 (0.67, 2.59)

0.417

1.37 (0.69, 2.72)

0.373

1.08 (0.51, 2.28)

0.835

 Tertile 3, (26.65 ± 6.74)

3.11 (1.40, 6.90)

0.005

3.52 (1.56, 7.95)

0.003

1.81 (0.73, 4.50)

0.200

Enhanced length > plaque length

8.80 (3.39, 22.85)

< 0.001

9.10 (3.48, 23.83)

< 0.001

6.77 (2.47, 18.51)

< 0.001

Enhancement quadrant

      

 0

1.0

 

1.0

 

1.0

 

 1

0.89 (0.22, 3.59)

0.873

0.91 (0.22, 3.76)

0.899

0.74 (0.17, 3.24)

0.686

 2

1.97 (0.50, 7.83)

0.336

1.76 (0.43, 7.22)

0.432

1.66 (0.38, 7.20)

0.501

 3

2.64 (0.68, 10.21)

0.160

2.30 (0.58, 9.17)

0.238

1.70 (0.39, 7.49)

0.481

 4

8.69 (2.35, 32.12)

0.001

8.00 (2.12, 30.16)

0.002

3.60 (0.83, 15.55)

0.086

  1. Non-adjusted model. Model 1 was adjusted for sex, age, BMI, hypertension, and diabetes; Model 2 was adjusted for model 1 plus intraplaque haemorrhage, plaque surface, enhanced grade, stenosis degree, remodelling index, and plaque burden