Dual-energy CT for the detection of skull base invasion in nasopharyngeal carcinoma: comparison of simulated single-energy CT and MRI

Zhan, Yang; Wang, Peng; Wang, Yuzhe; Wang, Yin; Tang, Zuohua

doi:10.1186/s13244-023-01444-3

Insights into Imaging

Table 3 Interobserver agreement in the evaluation of skull base invasions for SE-CT, MRI, and DECT in NPC patients

From: Dual-energy CT for the detection of skull base invasion in nasopharyngeal carcinoma: comparison of simulated single-energy CT and MRI

Parameter and reader	SECT images	MR images	DECT images
All sites (n = 300)
A versus B	0.77 (0.73–0.81)	0.83 (0.79–0.86)	0.84 (0.81–0.88)
A versus C	0.88 (0.85–0.91)	0.91 (0.89–0.94)	0.93 (0.91–0.95)
B versus C	0.89 (0.86–0.92)	0.92 (0.89–0.95)	0.91 (0.89–0.94)
D versus E	0.92 (0.89–0.94)
Sphenoid body (n = 50)
A versus B	0.80 (0.71–0.90)	0.83 (0.75–0.91)	0.88 (0.81–0.94)
A versus C	0.89 (0.82–0.96)	0.92 (0.87–0.97)	0.93 (0.88–0.98)
B versus C	0.92 (0.85–0.98)	0.91 (0.84–0.98)	0.94 (0.89–0.99)
D versus E	0.91 (0.85–0.97)
Clivus (n = 50)
A versus B	0.78 (0.69–0.87)	0.84 (0.75–0.92)	0.85 (0.78–0.92)
A versus C	0.89 (0.83–0.96)	0.92 (0.86–0.98)	0.93 (0.88–0.98)
B versus C	0.89 (0.82–0.96)	0.92 (0.85–0.98)	0.92 (0.88–0.96)
D versus E	0.94 (0.89–0.98)
Left pterygoid process (n = 50)
A versus B	0.76 (0.65–0.86)	0.80 (0.71–0.90)	0.83 (0.75–0.91)
A versus C	0.88 (0.80–0.96)	0.91 (0.84–0.97)	0.93 (0.87–0.98)
B versus C	0.86 (0.78–0.94)	0.90 (0.83–0.97)	0.90 (0.83–0.97)
D versus E	0.93 (0.87–0.99)
Right pterygoid process (n = 50)
A versus B	0.75 (0.62–0.88)	0.81 (0.72–0.91)	0.81 (0.72–0.91)
A versus C	0.89 (0.80–0.97)	0.88 (0.80–0.96)	0.91 (0.85–0.98)
B versus C	0.83 (0.72–0.94)	0.93 (0.87–0.99)	0.90 (0.82–0.98)
D versus E	0.89 (0.83–0.96)
Left Petrous apex (n = 50)
A versus B	0.76 (0.68–0.85)	0.83 (0.74–0.92)	0.80 (0.71–0.89)
A versus C	0.88 (0.81–0.96)	0.90 (0.84–0.97)	0.94 (0.89–0.99)
B versus C	0.88 (0.82–0.95)	0.93 (0.86–0.99)	0.86 (0.78–0.95)
D versus E	0.90 (0.83–0.97)
Right Petrous apex (n = 50)
A versus B	0.74 (0.63–0.84)	0.82 (0.73–0.92)	0.84 (0.76–0.93)
A versus C	0.85 (0.76–0.93)	0.91 (0.84–0.98)	0.93 (0.87–0.99)
B versus C	0.88 (0.81–0.97)	0.91 (0.84–0.98)	0.91 (0.85–0.98)
D versus E	0.92 (0.83–0.99)

Data are weighted K values with 95% confidence intervals. Weighted K values of less than 0 indicate poor agreement; 0–0.2, slight agreement; 0.21–0.4, fair agreement; 0.41–0.6, moderate agreement; 0.61–0.8, substantial agreement; and 0.81–1, almost perfect agreement

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