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Table 1 Quantitative dual-energy parameters between invaded bones in NPC patients and normal bones in control group

From: Dual-energy CT for the detection of skull base invasion in nasopharyngeal carcinoma: comparison of simulated single-energy CT and MRI

Parameter

Normalized iodine concentration

Effective atomic number

Invaded bonesa

Normal bonesa

t valuec

p valuec

Invaded bonesb

Normal bonesb

t valuec

p valuec

All lesions (n = 149)

 Sclerotic lesions (n = 90)

2.8 ± 0.8

2.2 ± 0.4

8.0

 < 0.0001*

10.6 ± 0.6

10.4 ± 0.5

2.8

0.007*

 Lytic lesions (n = 59)

1.6 ± 0.4

2.0 ± 0.4

8.1

 < 0.0001*

10.2 ± 0.5

10.4 ± 0.7

2.2

0.031*

Sphenoid body (n = 39)

 Sclerotic lesions (n = 26)

2.8 ± 1.0

2.2 ± 0.4

3.3

0.003*

10.8 ± 0.6

10.4 ± 0.5

2.8

0.011*

 Lytic lesions (n = 13)

1.6 ± 0.5

2.4 ± 0.5

4.8

 < 0.0001*

10.3 ± 0.5

10.5 ± 0.5

0.9

0.375

Clivus (n = 28)

 Sclerotic lesions (n = 13)

2.2 ± 0.6

1.8 ± 0.3

2.9

0.013*

10.4 ± 0.6

10.3 ± 0.6

0.4

0.706

 Lytic lesions (n = 15)

1.2 ± 0.3

1.6 ± 0.3

6.3

 < 0.0001*

10.0 ± 0.6

10.4 ± 0.9

2.1

0.058

Left pterygoid process (n = 28)

 Sclerotic lesions (n = 17)

3.2 ± 0.6

2.3 ± 0.4

7.2

 < 0.0001*

10.5 ± 0.6

10.4 ± 0.5

1.1

0.295

 Lytic lesions ( = 11)

1.9 ± 0.4

2.2 ± 0.3

3.4

0.007*

10.4 ± 0.6

10.5 ± 0.7

0.4

0.724

Right pterygoid process (n = 19)

 Sclerotic lesions (n = 12)

3.1 ± 0.8

2.4 ± 0.3

4.1

0.002*

10.4 ± 0.7

10.1 ± 0.2

1.4

0.198

 Lytic lesions (n = 7)

1.7 ± 0.2

2.1 ± 0.1

8.3

0.0002*

10.1 ± 0.2

10.1 ± 0.5

0.1

0.946

Left Petrous apex (n = 22)

 Sclerotic lesions (n = 13)

2.5 ± 0.6

2.1 ± 0.3

3.4

0.005*

10.3 ± 0.4

10.4 ± 0.5

0.4

0.701

 Lytic lesions (n = 9)

1.6 ± 0.2

1.9 ± 0.2

3.6

0.007*

10.4 ± 0.6

10.6 ± 0.7

0.8

0.469

Right Petrous apex (n = 13)

 Sclerotic lesions (n = 9)

2.4 ± 0.4

2.3 ± 0.1

1.3

0.238

10.7 ± 0.5

10.4 ± 0.5

2.8

0.023*

 Lytic lesions (n = 4)

1.9 ± 0.3

2.0 ± 0.2

5.7

0.608

10.2 ± 0.2

10.6 ± 0.4

1.8

0.180

  1. *Significant difference compared with nIC of normal bones (p < 0.05)
  2. aValue of normalized iodine concentration (nIC)
  3. bValue of effective atomic number (Zeff)
  4. cAs determined with paired t test