Short-term PET-derived kinetic estimation for the diagnosis of hepatocellular carcinoma: a combination of the maximum-slope method and dual-input three-compartment model

Insights into Imaging

Table 3 ¹⁸F-FDG PET-derived kinetic parameters of HCCs and background liver tissues by using the combined model

Parameters	HCC n = 24	Liver tissues n = 21	AUC	p
HPI (%)	76.43 ± 12.09	42.76 ± 17.08	0.937	< 0.001
K₁ (mL/min/mL)	1.52 ± 0.61	1.00 ± 0.63	0.750	0.007
k₂ (1/mL)	1.84 ± 0.56	1.01 ± 0.59	0.843	< 0.001
k₃ (1/mL)	0.046 ± 0.047	0.005 ± 0.007	0.866	< 0.001
k₄ (1/mL)	0.021 ± 0.027	0.023 ± 0.034	0.530	0.896
\({V}_{\mathrm{b}}\) (unitless)	0.052 ± 0.053	0.003 ± 0.007	0.810	< 0.001