Short-term PET-derived kinetic estimation for the diagnosis of hepatocellular carcinoma: a combination of the maximum-slope method and dual-input three-compartment model

Insights into Imaging

Table 2 ¹⁸F-FDG PET-derived kinetic parameters for HCCs and the background liver tissues by using the three-compartment model

Parameters	HCCs n = 24	Liver tissue n = 21	AUC	p
HPI (%)	71.14 ± 24.56	16.78 ± 20.29	0.944	< 0.001
K₁ (mL/min/mL)	1.67 ± 0.52	1.65 ± 0.73	0.511	0.927
k₂ (1/mL)	2.01 ± 0.43	1.66 ± 0.73	0.633	0.048
k₃ (1/mL)	0.051 ± 0.050	0.013 ± 0.021	0.784	0.003
k₄ (1/mL)	0.019 ± 0.027	0.023 ± 0.036	0.524	0.706
\({V}_{\mathrm{b}}\) (unitless)	0.081 ± 0.138	0.027 ± 0.056	0.649	0.098
SUVmax	5.320 ± 2.971	2.505 ± 0.629	0.859	< 0.001