MRI feature | No. of studies | Summary estimates | |||
---|---|---|---|---|---|
Sensitivity % (95% CI), I2% | Specificity % (95% CI), I2% | PLR (95% CI) | NLR (95% CI) | ||
Bulging prostatic contour | 6 | 53.0 (36.6–68.7), 82.2 | 83.1 (71.6–90.6), 81.5 | 3.1 (2.2–4.4) | 0.6 (0.4–0.7) |
Irregular or spiculated margin | 9 | 28.4 (16.3–44.7), 93.7 | 85.2 (79.3–89.6), 85.4 | 1.9 (1.2–3.0) | 0.8 (0.7–1.0) |
Asymmetry or invasion of neurovascular bundle | 7 | 28.0 (19.0–39.3), 75.5 | 95.1 (87.9–98.1), 92.3 | 5.7 (2.8–11.6) | 0.8 (0.7–0.8) |
Obliteration of rectoprostatic angle | 5 | 26.3 (14.8–42.2), 77.0 | 94.5 (88.6–97.4), 61.7 | 4.8 (3.0–7.5) | 0.8 (0.7–0.9) |
Tumor-capsule interface > 10 mm | 8 | 86.3 (70.0–94.4), 87.7 | 62.5 (47.3–75.6), 92.6 | 2.3 (1.7–3.1) | 0.2 (0.1–0.4) |
Breach of the capsule with direct tumor extension | 9 | 23.7 (14.8–35.8), 93.0 | 98.0 (96.2–99.0), 78.1 | 12.1 (6.4–23.0) | 0.8 (0.7–0.9) |