Table 2 Meta-analytic pooled diagnostic odds ratio of the individual MRI features of PI-RADS for extraprostatic extension
MRI feature | Number of studies | Number of observations | Summary estimates | P for publication bias | |
|---|---|---|---|---|---|
Pooled DOR (95% CI) | I2% | ||||
Bulging prostatic contour | 6 | 978 | 5.5 (3.8–8.0) | 98.4 | 0.81 |
Irregular or spiculated margin | 9 | 2377 | 2.3 (1.3–4.2) | 100.0 | 0.64 |
Asymmetry or invasion of neurovascular bundle | 7 | 1086 | 7.6 (3.8–15.2) | 89.9 | 0.32 |
Obliteration of rectoprostatic angle | 5 | 863 | 6.1 (3.8–9.8) | 48.6 | 0.55 |
Tumor-capsule interface > 10 mm | 8 | 2202 | 10.5 (5.4–20.2) | 100.0 | 0.16 |
Breach of the capsule with direct tumor extension | 9 | 2603 | 15.6 (7.7–31.5) | 98.5 | 0.09 |