Pretreatment synthetic magnetic resonance imaging predicts disease progression in nonmetastatic nasopharyngeal carcinoma after intensity modulation radiation therapy

Insights into Imaging

Table 1 Characteristics of NPC patients

Clinical characteristics	Disease progression group (n = 16)	Non-disease progression group (n = 37)	p value
Age	54.13 ± 8.45	48.08 ± 12.62	0.086
Gender			1.000
Male	13	29
Female	3	8
Histology			0.310
WHO II	8	13
WHO III	8	24
T stage			0.035
T1	0	10
T2	6	5
T3	5	14
T4	5	8
N stage			0.758
N0	1	6
N1	6	11
N2	4	9
N3	5	11
Clinical stage			0.847
I	0	1
II	3	8
III	5	11
IV	8	17
Treatment			1.000
IMRT	2	4
IMRT + chemotherapy	14	33
EBV DNA			0.311
< 4000	13	35
≥ 4000	3	2
LDH			0.686
< 182	9	23
≥ 182	7	14
SII			0.422
< 402.10	2	10
≥ 402.10	14	27
CRP			0.599
< 2.46	16	34
≥ 2.46	0	3

IMRT Intensity-modulated radiation therapy; EBV Epstein–Barr virus; LDH Lactate dehydrogenase; SII Systemic immune-inflammation index; CRP C-reactive protein