Table 2 Comparison of CT appearances of HEH lesions among different size groups
From: CT appearances and classification of hepatic epithelioid hemangioendothelioma
Parameters | Total (n = 740) | Small (n = 221) | Medium (n = 452) | Large (n = 67) | p value |
|---|---|---|---|---|---|
Size (cm) | 3.1 ± 2.4 | 1.4 ± 0.4 | 3.2 ± 1.2 | 8.4 ± 4.0 | < 0.001 |
Lesion Type | |||||
Nodular | 597 (80.7%) | 220 (99.5%) | 370 (81.9%) | 7 (10.4%) | < 0.001 |
Locally Coalescent | 122 (16.5%) | 1 (0.5%) | 81 (17.9%) | 40 (59.7%) | |
Diffusely Coalescent | 21 (2.8%) | 0 | 1 (0.2%) | 20 (29.9%) | |
Contour | |||||
Round | 279 (37.7%) | 139 (62.9%) | 136 (30.1%) | 4 (6.0%) | < 0.001 |
Round-like | 298 (40.3%) | 72 (32.6%) | 217 (48.0%) | 9 (13.4%) | |
Irregular | 127 (17.2%) | 8 (3.6%) | 76 (16.8%) | 43 (64.2%) | |
Strip-like/Flaky | 36 (4.9%) | 2 (0.9%) | 23 (5.1%) | 11 (16.4%) | |
Density on Plain Scan | |||||
Low | 711 (96.1%) | 195 (88.2%) | 449 (99.3%) | 67 (100%) | < 0.001 |
Equal | 29 (3.9%) | 26 (11.8%) | 3 (0.7%) | 0 | |
Target Sign on Plain Scan | |||||
Yes | 80 (10.8%) | 0 | 68 (15.0%) | 12 (17.9%) | < 0.001 |
No | 660 (89.2) | 221 (100%) | 384 (85.0%) | 55 (82.1%) | |
Subcapsular Lesion | |||||
Yes | 239 (32.3%) | 31 (14.0%) | 164 (36.3%) | 44 (65.7%) | < 0.001 |
No | 501 (67.7%) | 190 (86.0%) | 288 (63.7%) | 23 (34.3%) | |
Capsular Retraction | |||||
Yes | 88 (11.9%) | 3 (1.4%) | 59 (13.1%) | 26 (38.8%) | < 0.001 |
No | 652 (88.1%) | 218 (98.6%) | 393 (86.9%) | 41 (61.2%) | |
Lollipop Sign | |||||
Yes | 93 (12.6%) | 11 (5.0%) | 76 (16.8%) | 6 (9.0%) | < 0.001 |
No | 647 (87.4%) | 210 (95.0%) | 376 (83.2%) | 61 (91.0%) | |
Vascular Invasion | |||||
Yes | 51 (6.9%) | 0 | 25 (5.5%) | 26 (38.8%) | < 0.001 |
No | 689 (93.1%) | 221 (100%) | 427 (94.5%) | 41 (61.2%) | |
Calcification | |||||
Yes | 15 (2.0%) | 4 (1.8%) | 5 (1.1%) | 6 (9.0%) | < 0.001 |
No | 725 (98.0%) | 217 (98.2%) | 447 (98.9%) | 61 (91.0%) | |
Enhancement Pattern | |||||
Arterial | |||||
None | 398 (53.8%) | 189 (85.5%) | 196 (43.4%) | 13 (19.4%) | < 0.001 |
Ring | 56 (7.6%) | 23 (10.4%) | 33 (7.3%) | 0 | |
Target | 186 (25.1%) | 8 (3.6%) | 160 (35.4%) | 18 (26.9%) | |
Core | 13 (1.8%) | 1 (0.5%) | 12 (2.7%) | 0 | |
Heterogeneous | 87 (11.8%) | 0 | 51 (11.3%) | 36 (53.7%) | |
Portal | |||||
None | 312 (42.2%) | 164 (74.2%) | 142 (31.4%) | 6 (9.0%) | < 0.001 |
Ring | 32 (4.3%) | 16 (7.2%) | 16 (3.5%) | 0 | |
Target | 241 (32.6%) | 26 (11.8%) | 195 (43.1%) | 20 (29.9%) | |
Core | 23 (3.1%) | 4 (1.8%) | 19 (4.2%) | 0 | |
Heterogeneous | 132 (17.8%) | 11 (5.0%) | 80 (17.7%) | 41 (61.2%) | |
Equilibrium | |||||
None | 305 (41.2%) | 162 (73.3%) | 138 (30.5%) | 5 (7.5%) | < 0.001 |
Ring | 32 (4.3%) | 15 (6.8%) | 17 (3.8%) | 0 | |
Target | 240 (32.4%) | 28 (12.7%) | 191 (42.3%) | 21 (31.3%) | |
Core | 21 (2.8%) | 3 (1.4%) | 18 (4.0%) | 0 | |
Heterogeneous | 142 (19.2%) | 13 (5.9%) | 88 (19.5%) | 41 (61.2%) |