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Table 1 Clinical characteristics in the training and validation cohorts

From: Development of a simplified model and nomogram in preoperative diagnosis of pediatric chronic cholangitis with pancreaticobiliary maljunction using clinical variables and MRI radiomics

Variable

Training cohort (n = 100)

  

Validation cohort (n = 44)

  
 

Cholangitis (n = 39)

Non-cholangitis (n = 61)

p value

Cholangitis (n = 17)

Non-cholangitis (n = 27)

p value

Sex (%)

  

0.759

  

0.559

Male

10 (25.6)

14 (23.0)

 

4 (23.5)

4 (14.8)

 

Female

29 (74.4)

47 (77.0)

 

13 (76.5)

23 (85.2)

 

Age (mean ± SD) (years)

3.90 ± 3.32

3.46 ± 3.19

0.521

3.03 ± 2.61

3.69 ± 3.35

0.497

Komi classification (%)

  

0.112

  

0.381

Type I

17 (43.6)

28 (45.9)

 

9 (53.0)

12 (44.5)

 

Type II

20 (51.3)

22 (36.1)

 

8 (47.0)

13 (48.1)

 

Type III

2 (0.1)

11 (18.0)

 

0 (0.0)

2 (7.4)

 

Todani classification (%)#

  

0.387

  

0.353

Type I

22 (56.4)

29 (47.5)

 

7 (41.2)

15 (55.6)

 

Type IVa

17 (43.6)

32 (52.5)

 

10 (58.8)

12 (44.4)

 

Abdominal pain (%)

  

0.442

  

0.548

Yes

26 (66.7)

36 (59.0)

 

11 (64.7)

21 (77.8)

 

No

13 (33.3)

25 (41.0)

 

6 (35.3)

6 (22.2)

 

Jaundice (%)

  

0.040*

  

0.020*

Yes

18 (46.2)

16 (26.2)

 

8 (47.1)

3 (11.1)

 

No

21 (53.8)

45 (73.8)

 

9 (52.9)

24 (88.9)

 

Fever (%)

  

1.000

  

0.167

Yes

5 (12.8)

7 (11.5)

 

1 (5.9)

5 (18.5)

 

No

34 (87.2)

54 (88.5)

 

16 (94.1)

22 (81.5)

 

Vomiting (%)

  

0.098*

  

0.651

Yes

24 (61.5)

28 (45.9)

 

10 (9.3)

14 (51.9)

 

No

15 (38.5)

33 (54.1)

 

7 (7.7)

13 (48.1)

 

Protein plug (%)

  

0.030*

  

0.029*

Yes

22 (56.4)

14 (23.0)

 

10 (58.8)

7 (10.4)

 

No

17 (43.6)

47 (77.0)

 

7 (41.2)

20 (16.6)

 

Ascites (%)

  

0.000*

  

0.353

Yes

33 (84.6)

30 (49.1)

 

10 (58.8)

12 (44.4)

 

No

6 (15.4)

31 (50.9)

 

7 (41.2)

15 (55.6)

 

Liver dysfunction (%)

  

0.353

  

0.013*

Yes

24 (61.5)

43 (70.5)

 

15 (88.2)

14 (51.9)

 

No

15 (38.5)

18 (29.5)

 

2 (11.8)

13 (48.1)

 

Pancreatitis (%)

  

0.997

  

0.218

Yes

16 (41.0)

25 (41.0)

 

5 (29.4)

13 (48.1)

 

No

23 (59.0)

36 (59.0)

 

12 (70.6)

14 (51.9)

 

Elevated WBC count (%)

  

0.384

  

0.429

Yes

12 (30.8)

24 (36.3)

 

9 (52.9)

11 (40.7)

 

No

27 (69.2)

37 (60.7)

 

8 (47.1)

16 (59.3)

 
  1. *p < 0.1 SD standard deviation; WBC white blood cell
  2. #Almost all individuals with CBD of Todani Type I (except for Type Ib) and Type IVa have associated PBM, but types Ib, II, III, IVb, and V are not accompanied by PBM in almost all cases