Skip to main content

Table 2 Correlation analysis of FA difference values with respect to clinical features and lesion characteristics

From: Diffusion tensor imaging discriminates focal cortical dysplasia from normal brain parenchyma and differentiates between focal cortical dysplasia types

Clinical features and lesion characteristics

FA difference: FCD versus CBP

Correlation coefficient

p-value

Sex, median (IQR)#

  

1

 Male

0.008 (− 0.006 to 0.017)

  

 Female

0.049 (− 0.001 to 0.069)

  

Epilepsy duration in y§

 

 − 0.19 (− 0.57 to 0.18)

1

Age at MRI in y§

 

 − 0.15 (− 0.51 to 0.21)

1

Seizure frequency per month§

 

0.09 (− 0.22 to 0.43)

1

History of status epilepticus, median (IQR)#

  

0.004*

 Positive

0.012 (− 0.042 to 0.021)

  

 Negative

0.011 (− 0.00026 to 0.063)

  

Total ASD trials§

 

 − 0.12 (− 0.47 to 0.24)

1

Lesion lateralisation, mean ± SD+

  

1

 Right

0.020 ± 0.051

  

 Left

0.018 ± 0.039

  

Lobar localisation, median (IQR)#

  

0.79

 Temporal

0.013 (0.003 to 0.046)

  

 Extratemporal

0.003 (− 0.016 to 0.013)

  

Lesion volume in mm

 

 − 0.11 (− 0.44 to 0.29)

1

  1. FA: Fractional anisotropy, FCD: Focal cortical dysplasia, CBP: Contralateral brain parenchyma, IQR: Interquartile range, y: years, ASD: Anti-seizure drugs
  2. #Mann–Whitney U test
  3. +Welch t test
  4. §Spearman correlation coefficient
  5. *p < 0.05 statistical significance