CT and MR imaging features of mixed neuroendocrine–non-neuroendocrine neoplasm of the pancreas compared with pancreatic ductal adenocarcinoma and neuroendocrine tumor

Insights into Imaging

Table 3 Results of univariate and multivariate conditional logistic regression analyses for differentiating pancreatic MiNEN from PDAC or NET

Variables	Univariable analysis			Multivariable analysis
Variables	OR	95% CI	p value	OR	95% CI	p value
MiNEN versus PDAC
Tumor composition
Mixed solid and cystic	0.1	0.01–0.86	0.036
Heterogeneity	0.09	0.01–0.70	0.022	0.24	0.01–5.38	0.37
Moderate enhancement	0.05	0.01–0.41	0.005	0.08	0.01–0.69	0.022
Vascular involvement	4.65	1.22–17.65	0.024
MiNEN versus NET
Ill-defined irregular margin	0.05	0.01–0.39	0.004	0.1	0.01–0.94	0.044
Moderate enhancement	0.06	0.01–0.49	0.008	0.13	0.01–1.67	0.12
Portal progressive enhancement	0.12	0.01–1.02	0.052
Adjacent organ involvement	0.19	0.04–0.95	0.043

MiNEN, mixed neuroendocrine–non-neuroendocrine neoplasm; PDAC, pancreatic ductal adenocarcinoma; NET, neuroendocrine tumor; OR, odds ratio; CI, confidence interval