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Insights into Imaging
Fig. 18 | Insights into Imaging

Fig. 18

From: Multimodality imaging of neurodegenerative disorders with a focus on multiparametric magnetic resonance and molecular imaging

Fig. 18

A 81-year-old female with a gradual decline in short term memory and depression. Susceptibility-weighted image demonstrates numerous subcortical microhemorrhages (a). Fluorodeoxyglucose PET/MRI (b) demonstrates relatively normal cerebral metabolism. Later she presented with an acute worsening of symptoms including new right-side weakness and dysphasia. Magnetic resonance imaging demonstrated T2 FLAIR hyperintensity within the left frontal lobe (c) without restricted diffusion (d). Final diagnosis was amyloid beta-related angiitis. Cognitive function improved following administration of steroids. Fluorodeoxyglucose PET/MRI suggested against concurrent AD. Images from a separate patient demonstrate occipito-temporal subcortical microhemorrhages (e) with diffuse amyloid uptake on florbetapir PET/CT, a pattern suggesting concurrent CAA with AD (f)

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