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Fig. 3 | Insights into Imaging

Fig. 3

From: Predicting histologic differentiation of solitary hepatocellular carcinoma up to 5 cm on gadoxetate disodium-enhanced MRI

Fig. 3

Typical cases of poorly and moderately differentiated hepatocellular carcinoma (HCC). (a) A 61-year-old man with poorly differentiated HCC. (A) Rim hyperenhancement is visible on the arterial phase (arrow). (B) The portal venous phase shows an incomplete enhancing tumor capsule (arrow). (C) The signal intensity of the lesion on the hepatobiliary phase is less than vessels, showing marked hypointensity, and peritumoral hypointensity is also seen on the hepatobiliary phase (arrow). (D) Axial T2-weighted imaging shows a hyperintense signal lesion (arrow). (E) Diffusion weighted imaging shows a marked-restricted-diffusion lesion (arrow). (F) Photomicrograph shows the poorly differentiated HCC (hematoxylin–eosin stain; original magnification, × 100). (b) A 31-year-old man with moderately differentiated HCC. (A) Non-rim hyperenhancement is visible on the arterial phase (arrow). (B) The tumor present washout on the portal venous phase (arrow). (C)The lesion shows mild hypointensity on the hepatobiliary phase (arrow). (D) Axial T2-weighted imaging shows a hyperintense signal lesion (arrow). (E) Diffusion-weighted imaging shows a marked-restricted-diffusion lesion (arrow). (F) Photomicrograph shows the moderately differentiated HCC (hematoxylin–eosin stain; original magnification, 100)

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