Table 2 Summary of clinical and general imaging characteristics of literature review
Cases of the 15 studies | 180 |
|---|---|
Male/female | 3/5 (67/113) |
Mean/median age, years (11 studies) | 37.5–51.9 |
Clinical Presentation (11 articles, 78 cases) | |
Asymptomatic | 37/78 (47.4%) |
Abdominal pain | 17/78 (22.8%) |
Weight loss | 8/78 (10.3%) |
Abdominal distension | 5/78 (6.4%) |
Fatigue | 5/78 (6.4%) |
Others | 6/78 (7.7%) |
Past medical history and exposure history (13 articles, 161 cases) | |
HBV infection | 3/161 (1.9%) |
HCV infection | 3/161 (1.9%) |
Cirrhosis | 2/161 (1.2%) |
Surgical history | 2/161 (1.2%) |
Liver steatosis | 2/161 (1.2%) |
Others | 3/161 (1.9%) |
Tumour markers (10 articles, 51 cases) | |
CEA ↑ | 2/51 (3.9%) |
CA 125 ↑ | 1/51 (2.0%) |
AFP ↑ | 1/51 (2.0%) |
Liver enzymes (8 articles, 39 cases) | |
ALP ↑ | 4/39 (10.3%) |
GGT ↑ | 3/39 (7.6%) |
AST ↑ | 3/39 (7.6%) |
ALT ↑ | 1/39 (2.6%) |
Cases with imaging studies | 169 |
No. of CT | 121 (11 articles) |
No. of MRI | 103 (15 articles) |
Gd-EOB-DTPA | 20 (4 articles) |
Quantity | |
Multifocal | 143/169 (83.4%) |
Unifocal | 26/169 (15.4%) |
Size | |
Nodules | 139/169 (82.2%) |
Diffuse lesions | 4/169 (2.3%) |
Coalescent | 66/141 (46.8%) |
Calcification (9 articles, 119 cases) | 23/119 (19.3%) |
Extrahepatic HEHE (8 articles, 59 cases) | |
Lungs | 17/59 (28.8%) |
Bone | 5/59 (8.4%) |
Peritoneum | 1/59 (1.7%) |
Portal vein/hepatic vein invasion (9 articles, 118 cases) | 46/118 (3.9%) |