Fig. 11
T2 hyperintensity in supratentorial white matter—with neuronal migration abnormality (Pattern 4A). 2-week-old infant with multiple seizures and a bulging anterior fontanelle. CSF analysis was consistent with neurotoxoplasmosis. T2-weighted images (a, b, d) demonstrated diffuse white matter injury, widespread abnormal cortical development and hydrocephalus relating to aqueduct stenosis (arrow). Post-contrast T1-weighted imaging (c) demonstrated multiple peripherally enhancing lesions in the basal ganglia and periventricular regions, as well as enhancement of the ependymal lining of the lateral ventricles (reflecting ventriculitis)