Skip to main content

Table 5 Univariate and multivariate analysis of clinical and imaging factors for evaluating disease-free survival

From: MRI outcome evaluation in patients with IB2 and IIA2 squamous cervical cancer stages: preliminary results

Variables Univariate analysis Multivariate analysis
Cutoff values p value Exp(B)(95%CI) p value
Entire cohort
ADCmax 1.118  < 0.001 19.0 (6.5–55.1)  < 0.001
ADCmin 0.671  < 0.001 25.8 (9.3–71.7)  < 0.001
SCC-Ag 3.7 0.009 2.9 (1.2–7.1) 0.017
MDT 43.6 0.031 0.159
LNM 0.001 0.180
Age 51.5 0.110   
FIGO stage   0.705   
Pretreatment hemoglobin   0.887   
ADCmean 0.753  > 0.05   
NAT + RH group
ADCmin 0.671  < 0.001 6.2 (2.2–17.9) 0.001
SCC-Ag 4.7  < 0.001 5.0 (1.4–17.4) 0.011
Vascular invasion   0.007 4.2 (1.4–12.6) 0.011
Deep stromal invasion LNM   0.026   0.078
0.007 0.342
Age 42.5 0.153   
FIGO stage    > 0.05   
Pretreatment hemoglobin    > 0.05   
ADCmax 1.118  > 0.05   
ADCmean 0.755  > 0.05   
Operation method    > 0.05   
MDT 42.5 0.212   
CCRT group
ADCmax 1.113  < 0.001 11.2 (2.8–45.2) 0.001
ADCmin 0.649  < 0.001 5.5 (1.5–20.6) 0.010
MDT 47.8 0.004   0.059
LNM 0.036 0.732
Age 56.5 0.021   0.130
SCC-Ag 3.1 0.020   0.202
FIGO stage   0.289   
Pretreatment hemoglobin   0.973   
ADCmean 0.807  > 0.05   
  1. Bold values mean the differences were statistically significant
  2. NAT + RH neoadjuvant therapy followed by radical hysterectomy; CCRT concurrent chemoradiation; SCC-Ag squamous cell carcinoma antigen; MDT maximum tumor diameter; LNM lymph node metastasis; MDT is in unit of mm; ADC values are in units of 10−3mm2/s; and SCC-Ag is in unit of ng/ml