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Insights into Imaging

Table 5 Univariate and multivariate analysis of clinical and imaging factors for evaluating disease-free survival

From: MRI outcome evaluation in patients with IB2 and IIA2 squamous cervical cancer stages: preliminary results

Variables

Univariate analysis

Multivariate analysis

Cutoff values

p value

Exp(B)(95%CI)

p value

Entire cohort

ADCmax

1.118

 < 0.001

19.0 (6.5–55.1)

 < 0.001

ADCmin

0.671

 < 0.001

25.8 (9.3–71.7)

 < 0.001

SCC-Ag

3.7

0.009

2.9 (1.2–7.1)

0.017

MDT

43.6

0.031

0.159

LNM

0.001

0.180

Age

51.5

0.110

  

FIGO stage

 

0.705

  

Pretreatment hemoglobin

 

0.887

  

ADCmean

0.753

 > 0.05

  

NAT + RH group

ADCmin

0.671

 < 0.001

6.2 (2.2–17.9)

0.001

SCC-Ag

4.7

 < 0.001

5.0 (1.4–17.4)

0.011

Vascular invasion

 

0.007

4.2 (1.4–12.6)

0.011

Deep stromal invasion LNM

 

0.026

 

0.078

0.007

0.342

Age

42.5

0.153

  

FIGO stage

 

 > 0.05

  

Pretreatment hemoglobin

 

 > 0.05

  

ADCmax

1.118

 > 0.05

  

ADCmean

0.755

 > 0.05

  

Operation method

 

 > 0.05

  

MDT

42.5

0.212

  

CCRT group

ADCmax

1.113

 < 0.001

11.2 (2.8–45.2)

0.001

ADCmin

0.649

 < 0.001

5.5 (1.5–20.6)

0.010

MDT

47.8

0.004

 

0.059

LNM

0.036

0.732

Age

56.5

0.021

 

0.130

SCC-Ag

3.1

0.020

 

0.202

FIGO stage

 

0.289

  

Pretreatment hemoglobin

 

0.973

  

ADCmean

0.807

 > 0.05

  
  1. Bold values mean the differences were statistically significant
  2. NAT + RH neoadjuvant therapy followed by radical hysterectomy; CCRT concurrent chemoradiation; SCC-Ag squamous cell carcinoma antigen; MDT maximum tumor diameter; LNM lymph node metastasis; MDT is in unit of mm; ADC values are in units of 10−3mm2/s; and SCC-Ag is in unit of ng/ml
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