Table 2 Comparison of clinical indices, histopathologic factors and imaging indices among three different neoadjuvant therapy modalities followed by radical hysterectomy
Index | NAC + RH group (n = 31) | NAR + RH group (n = 28) | NACR + RH group (n = 27) | p value |
|---|---|---|---|---|
Age | 49.0 ± 9.1 | 51.1 ± 8.5 | 50.8 ± 8.6 | 0.601 |
FIGO | 0.359 | |||
IB2 | 11 | 15 | 11 | |
IIA2 | 20 | 13 | 16 | |
Pretreatment hemoglobin | 0.965 | |||
Normal | 24 | 21 | 21 | |
Abnormal | 7 | 7 | 6 | |
SCC-Ag | 3.8 (1.3, 9.3) | 3.1 (2.5, 4.9) | 2.5 (1.1, 8.8) | 0.766 |
ADCmax | 1.102 ± 0.114 | 1.099 ± 0.145 | 1.097 ± 0.143 | 0.954 |
ADCmean | 0.926 ± 0.123 | 0.897 ± 0.139 | 0.900 ± 0.141 | 0.622 |
ADCmin | 0.783 ± 0.111 | 0.761 ± 0.112 | 0.760 ± 0.123 | 0.575 |
LNM | 0.077 | |||
Positive | 5 | 4 | 10 | |
Negative | 26 | 24 | 17 | |
Vascular invasion | 0.745 | |||
Positive | 7 | 5 | 4 | |
Negative | 24 | 23 | 23 | |
Deep stromal invasion | 0.765 | |||
Positive | 12 | 10 | 8 | |
Negative | 19 | 18 | 19 | |
Operation method | 0.460 | |||
Pelvic lymphadenectomy | 21 | 21 | 16 | |
Pelvic + para-aortic lymphadenectomy | 10 | 7 | 11 |