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Table 2 Comparison of clinical indices, histopathologic factors and imaging indices among three different neoadjuvant therapy modalities followed by radical hysterectomy

From: MRI outcome evaluation in patients with IB2 and IIA2 squamous cervical cancer stages: preliminary results

Index NAC + RH group (n = 31) NAR + RH group (n = 28) NACR + RH group (n = 27) p value
Age 49.0 ± 9.1 51.1 ± 8.5 50.8 ± 8.6 0.601
FIGO     0.359
  IB2 11 15 11  
  IIA2 20 13 16  
Pretreatment hemoglobin     0.965
  Normal 24 21 21  
  Abnormal 7 7 6  
SCC-Ag 3.8 (1.3, 9.3) 3.1 (2.5, 4.9) 2.5 (1.1, 8.8) 0.766
ADCmax 1.102 ± 0.114 1.099 ± 0.145 1.097 ± 0.143 0.954
ADCmean 0.926 ± 0.123 0.897 ± 0.139 0.900 ± 0.141 0.622
ADCmin 0.783 ± 0.111 0.761 ± 0.112 0.760 ± 0.123 0.575
LNM     0.077
  Positive 5 4 10  
  Negative 26 24 17  
Vascular invasion     0.745
  Positive 7 5 4  
  Negative 24 23 23  
Deep stromal invasion     0.765
  Positive 12 10 8  
  Negative 19 18 19  
Operation method     0.460
  Pelvic lymphadenectomy 21 21 16  
  Pelvic + para-aortic lymphadenectomy 10 7 11  
  1. NAC + RH neoadjuvant chemotherapy followed by radical hysterectomy; NAR + RH neoadjuvant radiotherapy followed by radical hysterectomy; NACR + RH neoadjuvant chemoradiotherapy followed by radical hysterectomy; MDT maximum tumor diameter; SCC-Ag squamous cell carcinoma antigen