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Table 2 Clinical and radiological characteristics for benign and borderline EOTs in training set

From: T2-weighted MRI-based radiomics for discriminating between benign and borderline epithelial ovarian tumors: a multicenter study

Cohort

Benign (n = 224)

Borderline (n = 85)

p

Age (years)

45.76 ± 16.10

44.78 ± 16.01

0.634

Menopausal status

  

0.266

 Postmenopausal

116 (51.8)

38 (44.7)

 

 Premenopausal

108 (48.2)

47 (55.3)

 

Parity

  

0.887

 Multipara

186 (83.0)

70 (84.2)

 

 Nullipara

38 (17.0)

15 (17.6)

 

Abdominal symptoms

  

0.321

 Pain or distention

94 (42.0)

41 (48.2)

 

 None

130 (58.0)

44 (51.8)

 

CA125 (U/mL)

  

0.000*

 ≥ 35

35 (15.6)

43 (50.6)

 

 < 35

189 (84.4)

42 (49.4)

 

HE4a (pmol/L)

  

0.001*

 Abnormal

8 (3.6)

12 (14.1)

 

 Normal

216 (96.4)

73 (85.9)

 

Ascites

  

0.000*

 None

110 (49.1)

40 (47.1)

 

 Mild

98 (43.8)

29 (34.9)

 

 Moderate

15 (6.7)

7 (8.2)

 

 Massive

1 (0.4)

9 (10.6)

 

 Maximum tumor diameter (cm)

8.65 (6.22, 11.60)

10.40 (8.05, 13.65)

0.001*

Tumor margins

  

0.021*

 Well-defined

223 (99.6)

81 (95.3)

 

 Ill-defined

1 (0.4)

4 (4.7)

 

Number of loculi

  

0.107

 Mild

136 (60.7)

43 (50.6)

 

 Multilocular

88 (39.3)

42 (49.4)

 

SI of cystic on FS T2W

  

0.000*

 Moderate

182 (81.3)

48 (56.5)

 

 Low

10 (4.5)

17 (20.0)

 

 High

5 (2.2)

6 (7.1)

 

 Mixed

27 (12.1)

14 (16.5)

 

SI of solid on FS T2W

  

0.000*

 Low

41 (18.3)

42 (49.4)

 

 High

0 (0.0)

1 (1.2)

 

 Mixed

12 (5.4)

10 (11.8)

 

 None

171 (76.3)

32 (37.6)

 
  1. Data are presented as mean ± standard deviation for normally distributed continuous variables, median (interquartile range, IQR) for non-normally distributed continuous variables, or number (%) for categorical variables. HE4, human epididymis protein 4; CA125, carbohydrate antigen 125; SI, signal intensity; FS: fat-suppressed; T2W: T2 weighted
  2. *p < 0.05
  3. aNormal value of HE4: postmenopausal woman < 121 pmol/L or premenopausal < 92.1 pmol/L