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Table 4 Comparison of predictive performance for non-good pathological response between tumor volume, T2 and ADC values

From: T2 relaxation time for the early prediction of treatment response to chemoradiation in locally advanced rectal cancer

  Sensitivity (%) Specificity (%) Accuracy (%) Cutoff value AUC (95% CI)
ΔVduring 55 (11/20) 100 (21/21) 76 (31/41) 28% 0.79 (0.64–0.91)
ΔADCduring 90 (18/20) 67 (14/21) 78 (32/41) 19% 0.78 (0.63–0.90)
ΔT2during 90 (18/20) 86 (18/21) 88 (36/41) 11% 0.91 (0.78–0.98)
T2post 75 (15/20) 100 (21/21) 86 (36/41) 58 ms 0.90 (0.77–0.97)
  1. ΔADCduring: the relative early ADC increase from beginning to the end of radiotherapy; T2during: T2 relaxation time of MRI during CRT; T2post: T2 relaxation time of MRI post CRT; ΔT2during: the relative early T2 decrease from initiation to the end of radiotherapy