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Table 4 Comparison of predictive performance for non-good pathological response between tumor volume, T2 and ADC values

From: T2 relaxation time for the early prediction of treatment response to chemoradiation in locally advanced rectal cancer

 

Sensitivity (%)

Specificity (%)

Accuracy (%)

Cutoff value

AUC (95% CI)

ΔVduring

55 (11/20)

100 (21/21)

76 (31/41)

28%

0.79 (0.64–0.91)

ΔADCduring

90 (18/20)

67 (14/21)

78 (32/41)

19%

0.78 (0.63–0.90)

ΔT2during

90 (18/20)

86 (18/21)

88 (36/41)

11%

0.91 (0.78–0.98)

T2post

75 (15/20)

100 (21/21)

86 (36/41)

58 ms

0.90 (0.77–0.97)

  1. ΔADCduring: the relative early ADC increase from beginning to the end of radiotherapy; T2during: T2 relaxation time of MRI during CRT; T2post: T2 relaxation time of MRI post CRT; ΔT2during: the relative early T2 decrease from initiation to the end of radiotherapy