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Table 3 Comparison of T2 and ADC values between good responders and non-good responders and the correlation test

From: T2 relaxation time for the early prediction of treatment response to chemoradiation in locally advanced rectal cancer

  TRG 1–2 (median, interquartile distance) TRG 3–5 (median, interquartile distance) Mann–Whitney U (Z, P) Rank correlation with TRG (r, P)
Vpre (cc) 18.3 (11.2) 16.3 (10.9)  − 0.765, 0.445  − 0.202, 0.206
Vduring (cc) 10.0 (5.7) 10.2 (6.5) 0.652, 0.514  − 0.003, 0.983
Vpost (cc) 6.0 (2.8) 7.8 (6.0) 3.134, 0.002* 0.404, 0.008*
ΔVduring (%) 45.9 (15.6) 26.8 (21.0) 3.234. 0.001*  − 0.485, 0.001*
ADCpre (× 10−3 mm2/s) 1.21 (0.71) 1.24 (0.65)  − 1.601, 0.109 0.283, 0.073
ADCduring (× 10−3 mm2/s) 1.34 (0.21) 1.36 (0.56)  − 0.384, 0.701 0.026, 0.873
ΔADCduring (%) 25 (32) 10 (19)  − 2.914, 0.004* 0.485, 0.001*
T2pre (ms) 71.0 (5.0) 68.5 (13.0)  − 0.929, 0.350  − 0.108, 0.500
T2during (ms) 61.0 (5.0) 65.5 (9.0)  − 2.800, 0.005* 0.586, < 0.001*
T2post (ms) 53.0 (6.0) 61.0 (8.0) 4.390, < 0.001* 0.857, < 0.001*
ΔT2during (%) 13.9 (9.3) 4.5 (8.5)  − 4.474, < 0.001*  − 0.753, < 0.001*
  1. *p < 0.05
  2. Vpre: tumor volume at pre-treatment MRI; Vduring: tumor volume during CRT; Vpost: tumor volume after CRT; ΔVduring: the relative early tumor volume decreased from beginning to the middle of CRT; ADCpre: ADC values at pre-treatment MRI; ADCduring: ADC values of MRI during CRT; ΔADCduring: the relative early ADC increase from beginning to middle of CRT; T2pre: T2 relaxation time at pre-treatment MRI; T2during: T2 relaxation time of MRI during CRT; T2post: T2 relaxation time of MRI after CRT; ΔT2during: the relative T2 increase from initiation to the end of radiotherapy
  3. Cc, cubic centimeter; ms, millisecond