Evaluation of contrast-induced acute kidney injury using IVIM and DKI MRI in a rat model of diabetic nephropathy

Insights into Imaging

Table 4 Correlation analyses between the MRI parameters and laboratory test index, pathological score, and immunohistochemical expression

Spearman’s correlation (r, P)	D (× 10^–3 mm²/s)			D* (× 10^–3 mm²/s)			f (%)			MD (× 10^–3 mm²/s)			MK
Spearman’s correlation (r, P)	CO	OM	IM	CO	OM	IM	CO	OM	IM	CO	OM	IM	CO	OM	IM
SCr (μmol/L)	− 0.624, < 0.001	− 0.448, < 0.001	− 0.543, < 0.001	− 0.581, < 0.001	− 0.515, < 0.001	− 0.537, < 0.001	− 0.462, < 0.001	− 0.363, < 0.001	− 0.315, < 0.001	− 0.491, < 0.001	− 0.367, < 0.001	− 0.169, 0.051	0.118, 0.172	0.276, 0.001	0.137, 0.113
BUN (mmol/L)	− 0.234, 0.007	− 0.14, 0.11	− 0.194, 0.026	− 0.216, 0.013	− 0.196, 0.025	− 0.189, 0.03	− 0.15, 0.094	− 0.107, 0.233	− 0.093, 0.303	− 0.194, 0.024	− 0.094, 0.28	− 0.076, 0.384	0.02, 0.822	0.089, 0.302	0.181, 0.036
Pathology scores	− 0.784, < 0.001	− 0.623, < 0.001	− 0.775, < 0.001	− 0.674, < 0.001	− 0.616, < 0.001	− 0.583, < 0.001	− 0.568, < 0.001	− 0.510, < 0.001	− 0.273, 0.002	− 0.761, < 0.001	− 0.576, < 0.001	− 0.807, < 0.001	0.188, 0.029	0.452, < 0.001	0.268, 0.002
α-SMA	− 0.742, < 0.001	− 0.617, < 0.001	− 0.574, < 0.001	− 0.565, < 0.001	− 0.543, < 0.001	− 0.461, < 0.001	− 0.813, < 0.001	− 0.823, < 0.001	− 0.707, < 0.001	− 0.756, < 0.001	− 0.824, < 0.001	− 0.737, < 0.001	0.153, 0.077	0.399, < 0.001	0.209, 0.015