Table 4 Multivariate Cox regression analysis of disease-free survival (patients with adenocarcinoma)
Variable | Crude HR (95% CI) | Adjusted HR (95% CI) |
|---|---|---|
Sex (male) | 2.07 (1.29–3.33) | 1.94 (1.17–3.21) |
Age | 1.03 (1.00–1.06) | 1.01 (1.01–1.06) |
Surgery type | ||
Limited resection* | 1 (Ref.) | 1 (Ref.) |
Lobectomy | 1.59 (0.85–2.96) | 0.67 (0.33–1.36) |
Pathologic invasive size | 1.89 (1.49–2.42) | 1.31 (0.96–1.78) |
Pathologic nodal upstaging | 6.84 (4.20–11.14) | 3.69 (2.12–6.40) |
Predominant histologic pattern | 1.99 (1.17–3.38) | 0.79 (0.44–1.44) |
CTR | ||
CTR < 75% | 1 (Ref.) | 1 (Ref.) |
75% < CTR < 100% | 5.59 (2.20–14.17) | 5.36 (1.95–14.77) |
CTR = 100% | 11.01 (4.71–25.72) | 6.93 (2.65–18.17) |