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Insights into Imaging

Table 3 Multivariate Cox regression analysis of disease-free survival (all patients)

From: Reappraising the clinical usability of consolidation-to-tumor ratio on CT in clinical stage IA lung cancer

Variable

Crude HR (95% CI)

Adjusted HR (95% CI)

Sex (male)

2.18 (1.41–3.37)

1.70 (1.08–2.66)

Age

1.04 (1.02–1.06)

1.03 (1.01–1.05)

Surgery type

Limited resection*

1 (Ref.)

1 (Ref.)

Lobectomy

1.09 (0.66–1.80)

0.50 (0.29–0.87)

Pathologic invasive size

1.78 (1.43–2.22)

1.40 (1.07–1.84)

Histologic type (ADC)

0.43 (0.25–0.72)

1.03 (0.59–1.82)

Pathologic nodal upstaging

4.83 (3.05–7.63)

2.97 (1.81–4.89)

CTR

CTR < 75%

1 (Ref.)

1 (Ref.)

75% < CTR < 100%

4.92 (2.05–11.78)

4.35 (1.78–10.65)

CTR = 100%

9.76 (4.47–21.31)

6.41 (2.82–14.60)

  1. Adjusted for sex, age, surgery type, clinical T stage, histologic type, pathologic nodal upstaging for all subjects
  2. HR hazard ratio; CI confidence interval; ADC adenocarcinoma; and CTR consolidation-to-tumor ratio
  3. *Limited resection = wedge resection + segmentectomy
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