Table 1 Patient baseline characteristics
Characteristic | c/t ratio | p-value | ||||||
|---|---|---|---|---|---|---|---|---|
Variable | Overall (n = 944) | 0% (n = 89) | 0–25% (n = 81) | 25–50% (n = 83) | 50–75% (n = 116) | 75–100% (n = 201) | 100% (n = 374) | |
Sex, male | 444 (47.0%) | 36 (40.5%) | 36 (44.4%) | 39 (47.0%) | 47 (40.5%) | 77 (38.3%) | 209 (55.9%) | 0.001 |
Age, years | 61.9 ± 10.3 | 59.8 ± 8.5 | 60.2 ± 8.9 | 60.6 ± 9.6 | 61.1 ± 9.6 | 62.0 ± 10.1 | 63.2 ± 11.2 | 0.107 |
Smoking status | 0.002 | |||||||
Never smoker | 524 (55.5%) | 61 (68.5%) | 46 (56.8%) | 45 (54.2%) | 71 (61.2%) | 122 (60.7%) | 179 (47.9%) | |
Ever smoker | 420 (44.5%) | 28 (31.5%) | 35 (43.2%) | 38 (45.8%) | 45 (38.8%) | 79 (39.3%) | 195 (52.1%) | |
ECOG (n = 933) | ||||||||
0,1 | 931 (99.8%) | 89 (100.0%) | 81 (100.0%) | 81 (100.0%) | 114 (100.0%) | 197 (99.5%) | 369 (99.7%) | 0.899 |
2,3 | 2 (0.2%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1 (0.5%) | 1 (0.3%) | |
Tumor size | ||||||||
Total (mm, mean ± SD) | 21.7 ± 7.1 | 19.2 ± 6.1 | 19.2 ± 6.1 | 21.6 ± 7.8 | 24.6 ± 9.1 | 22.4 ± 7.6 | 21.5 ± 5.8 | 0.000 |
Solid portion (mm, mean ± SD) | 15.4 ± 9.2 | 0 | 3.2 ± 1.7 | 8.4 ± 3.6 | 15.2 ± 5.9 | 18.8 ± 6.4 | 21.5 ± 5.8 | 0.000 |
Clinical stage | ||||||||
IA1 | 280 (29.7%) | 89 (100%) | 81 (100%) | 64 (77.1%) | 27 (23.3%) | 17 (8.5%) | 2 (0.5%) | 0.000 |
IA2 | 350 (37.1%) | 0 | 0 | 19 (22.9%) | 68 (58.6%) | 110 (54.7%) | 153 (40.9%) | |
IA3 | 314 (33.3%) | 0 | 0 | 0 | 21 (18.1%) | 74 (36.8%) | 219 (58.6%) | |
Surgery type | ||||||||
Wedge resection | 145 (15.4%) | 33 (37.1%) | 19 (23.5%) | 21 (25.3%) | 15 (12.9%) | 15 (7.5%) | 42 (11.2%) | 0.000 |
Segmentectomy | 99 (10.5%) | 15 (16.9%) | 17 (21.0%) | 14 (16.9%) | 18 (15.5%) | 16 (8.0%) | 19 (5.1%) | |
Lobectomy | 700 (74.2%) | 41 (46.1%) | 45 (55.6%) | 48 (57.8%) | 83 (71.6%) | 170 (84.6%) | 313 (83.7%) | |
Follow-up period (months) | 30.8 (26.5–35.5) | 31.8 (27.1–36.1) | 28.8 (23.2–29.7) | 32.4 (27.3–36.7) | 30.4 (26.8–35.7) | 30.8 (26.5–35.9) | 30.8 (26–35.4) | 0.275 |