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Table 1 Study aims, injury to be detected and patient inclusion/exclusion criteria, organised by publication date

From: Artificial intelligence for radiological paediatric fracture assessment: a systematic review

Author, year

Country

Body part

Type of injury

Patient inclusion criteria

Patient exclusion criteria

Study aim

Zhou, [36]

USA

Forearm

Plastic bowing deformities

Forearm radiographs of children aged 1–18 years with history of trauma

None stated

Development of a computer-aided detection application for plastic bowing deformity fractures in paediatric forearms

Malek [32]

Malaysia

Lower limb (femur, tibia, fibula)

Any fracture

Radiographs of fractured femur, tibia or fibula in children < 12 years of age

None stated

Development of an artificial neural network to analyse normal (< 12 weeks) versus delayed healing time for paediatric lower limb fractures

England [31]

USA

Elbow

Traumatic elbow joint effusions

Elbow radiographs of children aged 1–19 years attending the emergency department with history of blunt trauma. Lateral view of radiograph technically adequate

Images with cast applied, elbow dislocation/displacement, comminuted fracture, metallic surgical hardware

Detection of traumatic paediatric elbow joint effusions using a deep convolutional neural network

Rayan [33]

USA

Elbow

Any elbow fracture

Elbow radiographs in children

None stated

Binomial classification of elbow fractures using a deep learning approach

Choi [17]

South Korea

Elbow

Supracondylar fractures

Elbow radiographs (two views) in children with suspected supracondylar fracture

Follow-up imaging (only initial radiographs included) Non-supracondylar fractures Elbow dislocation Underlying bone dysplasia

Development of a dual input convolutional neural network for detection of supracondylar fractures

Starosolski [34]

USA

Distal tibia

Most fracture types

Radiographs of the foot, ankle, tibia or fibula in children

Plastic bowing fractures or any fracture without discrete fracture line. Images with surgical fixation, cast or other alternative pathology than fracture

Development of a convolutional neural network for detection of tibial fractures

Dupuis [30]

France

Appendicular skeleton

Any appendicular fracture type

Radiographs of any body part from consecutive patients < 18 years old with suspected trauma attending emergency department

Radiographs of the axial skeleton (skull, spine, chest)

External validation of a commercially available deep learning algorithm for appendicular fracture detection in children

Zhang [35]

Canada

Distal radius

Any fracture type

Children aged < 17 years with unilateral distal radial tenderness following trauma with asymptomatic contralateral wrist as normal comparator

Existing cast over forearm, laceration of the forearm, open fractures, inability to tolerate ultrasound study, lack of time for scanning

Diagnostic accuracy of 3D ultrasound and use of artificial intelligence for detection of paediatric wrist injuries

Tsai [58]

USA

Distal tibia

Corner metaphyseal fractures

Children aged < 1 years referred for suspected abuse

None stated, AP projections for normal and abnormal distal tibial radiographs included only

Develop and evaluate a machine learning based binary classification algorithm to detect distal tibial corner metaphyseal fractures on radiographic skeletal surveys performed for suspected infant abuse