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Table 2 Hematocrit, extracellular volume (ECV) and left ventricular ejection fraction (LVEF) values at different time points

From: Myocardial extracellular volume derived from contrast-enhanced chest computed tomography for longitudinal evaluation of cardiotoxicity in patients with breast cancer treated with anthracyclines

 

Baseline

1–3 months

 ~ 6 months

 ~ 12 months

pa

pb

pc

(N0 = 1151)

(N1 = 1151)

(N2 = 841)

(N3 = 511)

Hematocrit (%)

39.26 ± 3.14

38.98 ± 2.16

37.66 ± 3.05

36.57 ± 2.51

0.099

 < 0.001

 < 0.001

ECV (%)

26.76 ± 3.03

31.32 ± 3.10

29.60 ± 3.24

32.05 ± 3.58

 < 0.001

 < 0.001

 < 0.001

LVEF (%)

65.85 ± 2.72

65.78 ± 2.87

65.55 ± 2.90

63.10 ± 6.51

0.637

0.394

 < 0.001

  1. pa: p value of hematocrit, ECV, LVEF compared with the baseline at 1–3 months
  2. pb: p value of hematocrit, ECV, LVEF compared with the baseline at 6 months
  3. pb: p value of hematocrit, ECV, LVEF compared with the baseline at 12 months