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Table 2 MRI protocol and assessment

From: Radiology–pathology correlation of endometrial carcinoma assessment on magnetic resonance imaging

Sequence

Plane (s)

Slice thickness

Tumour characteristics and what to look for

T1W

Axial T1W

5 mm

- Endometrial cancer is isointense to myometrium on T1W

- Haematometros is often seen post-biopsy and hyperintense

T2W

Sagittal T2W

4 mm

- Endometrial carcinoma has an intermediate signal on T2W

- Best sequences for anatomical delineation

- Assess depth of myometrial invasion and local staging

Axial T2W

4 mm

Oblique axial T2W

3 mm

DWI

Oblique axial DWI

(b50, 500, 800)

4 mm

- Endometrial carcinoma shows diffusion restriction

- Assess depth of myometrial invasion

- Detection of small tumour deposits in the cervix, adnexa, or vagina

- Detection of lymph nodes—however, does not distinguish between malignant and benign nodes

DCE and post-contrast T1W

Sagittal DCE T1W

3 mm

- Tumour enhancement is homogeneous, slower and less avid compared to the myometrium

- Early enhanced imaging helps in detecting junctional zone (subendometrial myometrium) to exclude myometrial invasion

- Loss of the normal rim of enhancement of the outer myometrium indicates serosal involvement

- Assess depth of myometrial invasion

- Assess presence of cervical or vaginal invasion

3D Axial T1W FS with oblique axial reformat

1 mm

  1. T1W T1-weighted, T2W T2-weighted, DWI diffusion-weighted imaging, DCE dynamic contrast-enhanced sequence, FS fat-saturated