Table 1 The demographics, clinical and pathological characteristics of patients in stable and impaired eGFR patients
From: Renal functional and interstitial fibrotic assessment with non-Gaussian diffusion kurtosis imaging
eGFR ≥ 60 | eGFR < 60 | p | |
|---|---|---|---|
(n = 23) | (n = 19) | ||
eGFR (ml/min/1.73 m2) | 90.9 ± 27.5 | 27.4 ± 13.8 | < 0.001 |
Male: Female | 13: 10 | 13: 6 | 0.429 |
Age (years) | 51 ± 23 | 48 ± 19 | 0.720 |
BMI (kg/m2) | 22.00 ± 4.56 | 22.48 ± 3.47 | 0.709 |
MAP (mmHg) | 96 ± 23 | 116 ± 18 | 0.005 |
Blood glucose* (mmol/L) | 5.53 (4.40–15.18) | 5.42 (4.10–13.37) | 0.487 |
Urea (mmol/L) | 5.65 ± 1.87 | 12.89 ± 6.34 | < 0.001 |
Serum creatinine (µmol/L) | 79 ± 19 | 284 ± 164 | < 0.001 |
Cystatin C (mL) | 1.27 ± 0.44 | 4.06 ± 2.04 | 0.017 |
24 h urine volume (mL) | 1836 ± 1288 | 1728 ± 524 | 0.811 |
24 h urinary mTP (mg/L) | 498.5 ± 375.0 | 4760.5 ± 4653.7 | 0.018 |
24 h urinary mALB (mg/L) | 286.1 ± 259.7 | 3104.9 ± 2705.0 | 0.009 |
Urine creatinine (µmol/L) | 4839.56 ± 5296.71 | 5593.14 ± 5797.25 | 0.772 |
UALB/Cr (µg/mg) | 331.31 ± 425.66 | 2569.15 ± 2711.16 | 0.016 |
Interstitial fibrosis† (n = 12) | 0.001 | ||
< 25% | 7 (100%) | 0 (0%) | |
25–50% | 0 (0%) | 0 (0%) | |
> 50% | 0 (0%) | 5 (100%) |