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Table 2 Association of selected radiomic features with semantic characteristics of lung cancer

From: Quantifying lung cancer heterogeneity using novel CT features: a cross-institute study

Feature

Solid

Lobular

Spiculated

Juxtapleural

Pleura tag

Circularity

  

↓A**

↑P*;↑A**;↑B*

↓A**

Variance

↑A**

 

↑P**;↑A*

↓B**

↑A*

Kurtosis

↓A**

 

↓P*

↓A**;↓B*

↑A**

Energy

↑A**

  

↑P**;↑A**

↓A**

Cluster-shade

 

↓A*

↓P*

↑C*

↓B*

Maximum-probability

↑P**;↑A**

↓P*

 

↑A**

 

LongHEM

↑A**

 

↑P*;↓C*

↑A*;↑C**

↑P*

A_Long-run emphasis

↓P*

 

↑A**

 

↓C*

  1. ↑ and ↓ denote up- and down-regulation of the feature in the presence of the semantic characteristics, respectively
  2. A, B, C, P denote statistically significant (* p < 0.050; ** p < 0.010) association observed in cohorts A, B, C and the proof-of-concept cohort, respectively
  3. LongHEM, long-run high gray-level emphasis mean