From: Quantifying lung cancer heterogeneity using novel CT features: a cross-institute study
Characteristics | Cohort A (N = 143) | Cohort B (N = 61) | Cohort C (N = 32) | p value |
---|---|---|---|---|
Male, n (%) | 108 (75.5) | 31 (50.8) | 16 (50.0) | 0.0004 |
Mean age, years (range) | 69.3 (43–87) | NA† | 62.1 (29–82) | – |
Cancer location | 0.2765 | |||
Left upper lobe | 38 (26.6) | 20 (32.8) | 4 (12.5) | |
Left lower lobe | 20 (14.0) | 8 (13.1) | 6 (18.8) | |
Right upper lobe | 51 (35.7) | 21 (34.4) | 9 (28.1) | |
Right middle lobe | 13 (9.1) | 5 (8.2) | 3 (9.4) | |
Right lower lobe | 21 (14.7) | 7 (11.5) | 10 (31.3) | |
Semantic characteristics | ||||
Solid | 90 (62.9) | 31 (50.8) | 26 (81.3) | 0.0155 |
Lobular | 96 (67.1) | 42 (68.9) | 21 (65.6) | 0.9470 |
Spiculated | 35 (24.5) | 17 (27.9) | 12 (37.5) | 0.3218 |
Juxtapleural | 59 (41.3) | 23 (37.7) | 19 (59.4) | 0.1121 |
Pleura tag | 28 (19.6) | 14 (23.0) | 5 (15.6) | 0.6936 |
Cancer stage | 0.0617 | |||
0-IIB | 118 (82.5) | 41 (70.7)‡ | NA | |
IIIA–IVB | 87 (17.5) | 17 (29.3) | NA | |
Median survival (IQR), month | 62.8 (45.9, 72.5) | 40.0 (31.0, 49.0) | NA | 0.0636 |