Fig. 3

Osteosarcoma involving the proximal metaphysis of the tibia in a 13-year-old boy. a Coronal fat-suppressed T2-weighted MR image shows a heterogeneous bone lesion (*) associated with a soft-tissue mass (arrow). b Axial ADC MR image shows diffusion restriction within the tumor (*). c, d Post-chemotherapy MRI. c Coronal fat-suppressed T2-weighted MR image shows a peripheral hypointense rim in the tumor suggestive of calcification (arrow). d Axial ADC MR image shows decrease of the areas of diffusion restriction (*) compared to the initial study, indicating good treatment response