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Table 7 Key features of each subtype of parasagittal central hypoxic–ischaemic injury

From: A proposed magnetic resonance imaging grading system for the spectrum of central neonatal parasagittal hypoxic–ischaemic brain injury

Substrate injury

Mild/Mod/Sev (N = 64)

MPI (N = 19)

Overall (N = 83)

P value

IHF Widening, n (%)

Other

6 (31.6)

55 (85.9)

61 (73.5)

< 0.001

 

Severe

13 (68.4)

9 (14.1)

22 (26.5)

 

Pre-central Gyrus Score, n (%)

Other

1 (5.3)

49 (76.6)

50 (60.2)

< 0.001

 

Severe

18 (94.7)

15 (23.4)

33 (39.8)

 

Post-Central Gyrus Score, n (%)

Other

4 (21.1)

52 (81.3)

56 (67.5)

< 0.001

 

Severe

15 (78.9)

12 (18.8)

27 (32.5)

 

SFG Score, n (%)

Other

18 (94.7)

62 (96.9)

80 (96.4)

0.547

 

Severe

1 (5.3)

2 (3.1)

3 (3.6)

 

Paracentral Lobule Score, n (%)

Other

1 (5.3)

45 (70.3)

46 (55.4)

< 0.001

 

Severe

18 (94.7)

19 (29.7)

37 (44.6)

 

Thalamus Score, n (%)

Other

3 (15.8)

37 (57.8)

40 (48.2)

0.002

 

Severe

16 (84.2)

27 (42.2)

43 (51.8)

 

Putamen Score, n (%)

Other

1 (5.3)

38 (59.4)

39 (47.0)

< 0.001

 

Severe

18 (94.7)

26 (40.6)

44 (53.0)

 

Heschl Gyrus, n (%)

Other

15 (78.9)

60 (93.8)

75 (90.4)

0.076

 

Severe

4 (21.1)

4 (6.3)

8 (9.6)

 

Insular Cortex, n (%)

Other

13 (68.4)

60 (93.8)

73 (88.0)

0.008

 

Severe

6 (31.6)

4 (6.3)

10 (12.0)

 

Hippocampus Score, n (%)

Other

2 (10.5)

30 (46.9)

32 (38.6)

0.006

 

Severe

17 (89.5)

34 (53.1)

51 (61.4)

 

Cerebellum, n (%)

Normal

12 (63.2)

47 (73.4)

59 (71.1)

0.400

 

Involved

7 (36.8)

17 (26.6)

24 (28.9)

 
  1. IHF interhemispheric fissure, SFG superior frontal gyrus, other lower grades of substrate injuries, Mod moderate subtype, Sev severe subtype, MPI massive paramedian injury