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Insights into Imaging

Table 3 Factors associated with patients’ progression-free survival

From: Prognostic role of computed tomography-based, artificial intelligence-driven waist skeletal muscle volume in uterine endometrial carcinoma

Characteristics

N

Univariate analysis

Multivariate analysis

HR

95% CI

P

aHR

95% CI

P

Age, years

   < 55

175

1

–

–

1

–

–

   ≥ 55

210

2.338

1.394–3.921

0.001

1.916

1.108–3.312

0.020

Histologic type

  Endometrioid

315

1

–

–

1

–

–

  Non-endometrioid

70

5.291

3.300–8.484

 < 0.001

1.572

0.794–3.111

0.194

Grade

  Low-grade

279

1

–

–

1

–

–

  High-grade

106

5.582

3.461–9.003

 < 0.001

1.876

0.926–3.800

0.081

FIGO stage

  I-II

295

1

–

–

1

–

–

  III-IV

90

5.291

3.308–8.464

 < 0.001

2.247

1.273–3.965

0.005

Adjuvant treatment

  No

229

1

–

–

1

–

–

  Yes

156

6.929

3.915–12.263

 < 0.001

2.888

1.468–5.683

0.002

BMI, kg/m2

  Underweight to normal (< 23.0)

132

1

–

–

1

–

–

  Overweight (23.0–24.9)

87

0.422

0.202–0.885

0.022

0.570

0.271–1.198

0.138

  Obesity (≥ 25.0)

166

0.738

0.449–1.215

0.233

1.127

0.670–1.897

0.651

Volumetric SMI

  High

193

1

–

–

1

–

–

  Low

192

2.004

1.231–3.261

0.005

1.762

1.051–2.953

0.032

  1. Abbreviations: aHR, adjusted hazard ratio; BMI, body mass index; CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics; HR, hazard ratio; SMI, skeletal muscle index
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