Fig. 1

CMR characteristics and genetics in LVNC. a The orange line identifies the thickness of the compacted layer, and the blue line identifies the thickness of the trabeculated layer. Standard epicardial contours (green line) and endocardial contours (red line) for measurement of the compacted myocardial mass and the papillary muscles (yellow line, pink line) were included from the measurements. Endocardial contours (red line) at the border of the non-compacted myocardium for measurement of the ‘global myocardial mass.’ The non-compacted mass (orange region) was subsequently calculated by subtracting compacted mass and papillary muscle mass from global LV myocardial mass. b Spectrum of pathogenic variants in this cohort