Fig. 3
From: Imaging features of primary sites and metastatic patterns of angiosarcoma
53-year-old woman with angiosarcoma associated with congenital lymphoedema of the left leg (Stewart–Treves syndrome). a Sagittal T2-weighted fat-suppressed image shows diffuse circumferential oedematous changes within the subcutaneous tissues and skin thickening in the left leg. There are multiple well-circumscribed nodules in the anterior proximal leg which are of predominantly low signal intensity compared to the surrounding tissues (arrow). b–d Axial images of the left leg show skin thickening and multiple soft tissue nodules (white arrows) within the oedematous subcutaneous tissues with a further intramuscular nodule (black arrow) within the lateral muscular compartment of the leg. b Axial T2-weighted image shows the nodules to be of heterogeneously lower signal compared to the adjacent oedematous subcutaneous tissues and higher signal compared to the skeletal muscles with central low signal striations. c Axial T1-weighted fat-suppressed pre-contrast image shows the nodules to be isointense compared to the skeletal muscles. d Axial T1-weighted fat-suppressed post-contrast image shows avid heterogeneous enhancement of the nodules within the subcutaneous tissues (white arrows) and the lateral muscular compartment (black arrow). e Photomicrograph shows a specimen composed predominantly of epithelioid cells, is seen to prominently infiltrate the dermal collagen and the subcutaneous adipose tissue (top right). Much of the tumour is disposed in solid nests, but small areas of vasoformation are discernible (H and E, × 200)