Fig. 1
From: Imaging features of primary sites and metastatic patterns of angiosarcoma
Histopathological features of angiosarcoma. a Photomicrograph of histologic specimen shows extensive, poorly formed, anastomosing vascular channels containing prominent blood. The channels are lined by moderately atypical ovoid cells with vesicular nuclei and prominent nucleoli (H and E, × 100). b Photomicrograph of histologic specimen shows a predominantly solid architecture without apparent vascular channel formation, but shows diffuse and strong expression of the vascular endothelial marker CD31. CD31 immunohistochemistry is seen to highlight small vascular channels within the mostly solid configuration of the tumour (immunohistochemistry, × 200)