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Table 1 MR imaging parameters details

From: Using amide proton transfer-weighted MRI to non-invasively differentiate mismatch repair deficient and proficient tumors in endometrioid endometrial adenocarcinoma

Parameters APTw T1-weighted T2-weighted T2-weighted Diffusion-weighted
Imaging acquisition 3D TSE TSE TSE TSE EPI
Orientation Axial Axial Axial Sagittal Axial
Repetition time/echo time (ms) 7188/5.4 507/8.0 3471/100 3500/100 4656/82
Flip angle (°) 90 90 90 90 90
Field of view (mm2) 300 × 243 240 × 300 400 × 400 260 × 260 300 × 218
Matrix (frequency × phase) 120 × 96 320 × 299 400 × 400 512 × 512 100 × 72
Spatial resolution (mm2) 2.5 × 2.5 0.75 × 1.0 1.0 × 1.0 0.51 × 0.51 3.0 × 3.0
Slice thickness (mm) 5 4 3 3 4
Slice gap (mm) 0 1 0.3 0.3 1
No. of slices 9 40 41 29 25
ETL 158 4 24 32
EPI factor 55
SENSE factor 2 1.6 3.5 1.5 1.8
b values 0,1000
Fat suppression SPIR SPAIR
Total image time (min:s) 7:33 3:18 2:36 3:21 1:30
  1. MR = Magnetic resonance; APTw = Amide proton transfer-weighted; TSE = Turbo spin echo; ETL = Echo train length; EPI = Echo planar imaging; SENSE = Sensitivity encoding; SPAIR = Spectral attenuation with inversion recovery; SPIR = Spectral presaturation with inversion recovery. Other key parameters for APTw imaging include 2-s long radiofrequency (RF) pulses at 2-μT power, and 9 acquisitions including 7 different frequency saturation offsets (− 4.3, − 3.5, − 2.7, 2.7, 3.5, 4.3 and − 1560 ppm) and 2 additional acquisitions with echo shifts