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Table 4 Studies classified by pCR-definition

From: Factors affecting the value of diffusion-weighted imaging for identifying breast cancer patients with pathological complete response on neoadjuvant systemic therapy: a systematic review

pCR-definition/first author

pCR rate (95% CI)

Na

Totalb

No invasive. No DCIS

Santamaria [27]

0.19 (0.12–0.26)

21

111

Minarikova (baseline) [59]

0.17 (0.05–0.28)

7

42

Minarikova (after 5 cycles) [59]

0.15 (0.03–0.27)

5

33

Woodhams [64]c

0.13 (0.05–0.21)

9

70

No invasive. DCIS may be present

Che [19]

0.19 (0.07–0.32)

7

36

Bedair [20]

0.39 (0.23–0.55)

14

36

Fangberget [65]

0.37 (0.19–0.54)

11

30

Shin [26]

0.37 (0.22–0.51)

15

41

Hahn [67]

0.24 (0.15–0.34)

19

78

Yuan [22]

0.28 (0.21–0.36)

40

142

Partridge (pre) [23]

0.31 (0.25–0.37)

71

227

Partridge (mid) [23]

0.33 (0.27–0.40)

70

210

Partridge (post) [23]

0.34 (0.27–0.41)

63

186

Gallivanone [21]d

0.42 (0.25–0.59)

13

31

Fujimoto [66]

0.14 (0.05–0.23)

8

56

Woodhams [64]e

0.13 (0.23–0.33)

16

70

Pereira [18]

0.39 (0.27–0.51)

24

62

No invasive (without specification)

Bufi [17]

0.17 (0.12–0.22)

39

225

Ramirez-Galván [25]f

0.25 (0.04–0.46)

4

16

Li [44]

0.33 (0.19–0.48)

14

42

Near pCR

Liu [16]g

0.18 (0.12–0.24)

32

176

Kim [53]g

0.30 (0.17–0.44)

14 (5: real pCR)

46

No definition for pCR

Tozaki [40]

0.14 (0–0.40)

1

7

  1. pCR pathologic complete response, DCIS ductal carcinoma in situ, CI confidence interval
  2. aLesions/patients with a pCR
  3. bTotal lesions/patients
  4. cData extracted from supplementary material
  5. dCalculated from 42% pCR from full-text
  6. eBroader pCR-definition including DCIS, in addition to original pCR-definition in full-text. Data extracted by supplementary materials
  7. fMiller and Payne grade 5
  8. gMiller and Payne 4 included, in Kim et al. [53] was labeled as good responders