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Table 1 Comparison of clinical characteristics between L-PLADC and D-PLADC

From: Pneumonic-type lung adenocarcinoma with different ranges exhibiting different clinical, imaging, and pathological characteristics

Characteristic Patients with L-PLADC (n = 131) Patients with D-PLADC (n = 117) p value
Age (years)    
 Means ± standard deviations 62 ± 9 61 ± 11 0.404a
 Range 35–62 23–84  
Sex    
 Male 43/131 (32.8%) 72/117 (61.5%) < 0.001b
 Female 88/131 (67.2%) 45/117 (38.5%)  
Smoking    
 Non-smokers 97/131 (74.0%) 52/117 (44.4%) < 0.001b
 Smokers 34/131 (26.0%) 65/117 (55.6%)  
Respiratory symptoms    
 Fever 7/131 (5.3%) 9/117 (7.7%) 0.452b
 Cough 54/131 (41.2%) 103/117 (88.0%) < 0.001b
 Sputum 42/131 (32.1%) 77/117 (65.8%) < 0.001b
 Blood in sputum 13/131 (9.9%) 13/117 (11.1%) 0.761b
 Hemoptysis 8/131 (6.1%) 11/117 (9.4%) 0.330b
 Chest pain 16/131 (12.2%) 13/117 (11.1%) 0.787b
 No symptoms 62/131 (47.3%) 5 /117 (4.3%) < 0.001b
Laboratory results    
 Elevation of white blood cell count 13/131 (9.9%) 41/117 (35.0%) 0.003b
 Elevation of C-reactive protein level c 10/32 (31.3%) 66/84 (78.6%) < 0.001b
  1. L-PLADC, localized pneumonic-type lung adenocarcinoma; D-PLADC, diffuse pneumonic-type lung adenocarcinoma
  2. aTwo independent samples Student’s t test
  3. bChi-squared test
  4. cC-reactive protein level was not assessed in 132 patients who did not undergo this test