|
Classifier
|
SVM-LASSO
|
SVM-RFE
|
SVM-ReliefF
|
|---|
|
Training cohort
|
Validation cohort
|
Testing cohort
|
Training cohort
|
Validation cohort
|
Testing cohort
|
Training cohort
|
Validation cohort
|
Testing cohort
|
|---|
|
AUC
|
0.838 [0.721–0.934]
|
0.795 [0.674–0.899]
|
0.754 [0.652–0.889]
|
0.842 [0.747–0.945]
|
0.803 [0.687–0.904]
|
0.761 [0.648–0.893]
|
0.860 [0.759–0.963]
|
0.824 [0.736–0.915]
|
0.787 [0.710–0.892]
|
|
Accuracy (%)
|
76.70 [68.05–85.26]
|
73.94 [73.49–89.75]
|
68.78 [55.67–82.89]
|
77.36 [65.35–86.25]
|
74.11 [62.98–87.19]
|
71.58 [59.87–83.74]
|
83.61 [75.85–92.65]
|
77.14 [69.38–86.05]
|
73.42 [61.63–82.66]
|
|
Sensitivity (%)
|
77.57 [64.45–87.31]
|
73.48 [60.67–86.48]
|
70.07 [61.71–82.99]
|
80.33 [69.35–89.79]
|
75.47 [63.78–89.36]
|
71.25 [61.36–80.74]
|
84.78 [74.36–93.74]
|
78.72 [64.35–91.48]
|
82.15 [73.74–91.92]
|
|
Specificity (%)
|
81.22 [72.19–89.24]
|
79.63 [61.34–70.49]
|
80.30 [71.58–89.43]
|
84.31 [73.74–92.18]
|
83.04 [71.39–95.46]
|
79.22 [66.57–88.34]
|
82.67 [74.35–93.14]
|
80.33 [69.74–92.26]
|
76.48 [63.36–89.17]
|
|
PPV (%)
|
76.88 [62.38–85.69]
|
73.86 [59.67–88.74]
|
69.71 [60.98–78.35]
|
79.46 [64.38–91.59]
|
74.78 [62.88–86.74]
|
72.98 [67.64–83.35]
|
77.79 [69.16–85.97]
|
75.98 [68.30–83.57]
|
74.82 [65.87–83.64]
|
|
NPV (%)
|
84.12 [76.41–95.37]
|
80.48 [71.70–92.26]
|
79.25 [66.28–91.33]
|
85.34 [75.65–96.43]
|
83.92 [74.54–91.35]
|
80.25 [72.36–92.17]
|
83.90 [72.74–95.46]
|
80.43 [71.32–89.91]
|
82.62 [71.64–92.35]
|
- Data in parentheses are 95% confidence intervals
- PPV positive predictive value, NPV negative predictive value
