Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles

Insights into Imaging

Table 2 Diastolic parameters with TPM included into myocardium for calculating normal values as significant function of age

Parameter	p	Function of age (= x)	a0	a1	a2	r²	SEE
LVpreAi	7.6E-04	a0 + a1∙x	77.2	− 0.42		0.28	12.1
DVR%	p < 10^–6	a0 (1 − exp(− x/a1)) + a2	69.1	30.8	18.6	0.64	9.50
EPFR/SV	p < 10^–6	a0∙exp(− x/a1)	7.45	82.3		0.64	0.76
APFRi	p < 10^–6	a0∙exp(− x/a1)	7.45	82.3		0.64	0.76
PFRR	p < 10^–6	a0∙exp(− x/a1)	8.9	24.4		0.85	0.66
FVR	p < 10^–6	a0∙exp(− x/a1)	11.2	27.9		0.89	0.72
TPFR (ms)	4.5E−04	a0 (1 − exp(− x/a1)) + a2	74.7	21.5	90.2	0.30	19.1
DT (ms)	4.0E−06	a0 (1 − exp(− x/a1)) + a2	63.9	22.4	84.6	0.14	24.2

LVpreA, time-volume at EA_min; EA_min, minimum between Early and Atrial peak relative to APFR; DVR%, diastolic volume recovery (percentage to diastole); EPFR/SV, early peak filling rate/stroke volume; APFR, atrial peak filling rate; PFRR, peak filling rate ratio; FVR, filling volume ratio; TPFR, time to peak filling rate; DT, deceleration time; i, indexed parameter
Spearman rank correlation probabilities (p), coefficients a0–a2, coefficient of determination r², and standard error of estimate (SEE)