Table 3 Radiogenomic features of pediatric brain tumors biomarkers
From: Clinical applications of artificial intelligence and radiomics in neuro-oncology imaging
| Â | Genetic biomarker | Features |
|---|---|---|
1—Medulloblastoma | SHH |  |
Wingless-type |  ~ 90% 5-year survival rate | |
Group 3 |  < 50% overall survival | |
Group 4 | Â | |
2—PLGG | BRAF fusion | Favorable outcome |
BRAF V600E | High risk of progression | |
3—DMG | H3 K27M mutation | Shorter median survival |
Wild-type H3 K27M | Improved survival |