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Table 3 Radiogenomic features of pediatric brain tumors biomarkers

From: Clinical applications of artificial intelligence and radiomics in neuro-oncology imaging

  Genetic biomarker Features
1—Medulloblastoma SHH  
Wingless-type  ~ 90% 5-year survival rate
Group 3  < 50% overall survival
Group 4  
2—PLGG BRAF fusion Favorable outcome
BRAF V600E High risk of progression
3—DMG H3 K27M mutation Shorter median survival
Wild-type H3 K27M Improved survival
  1. SHH sonic hedgehog, PLGGs pediatric low-grade gliomas, DMG diffuse midline gliomas