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Table 1 Frequency and location of MS damages in the brainstem

From: The brainstem in multiple sclerosis: MR identification of tracts and nuclei damage

Structure Medulla Pons Midbrain Abbreviations Label
Cortico-spinal tract 8 (16%) 12 (24%) 6 (12%) CST 1
Medial lemniscus 7 (14%) 10 (20%) 7 (14%) ML 2
Cuneate and gracile fasciculi 5 (10%)    CFGF 2.1
Internal arcuate fibers 5 (10%)    IAF 2.2
Spino thalamic tract 9 (18%) 22 (44%) 11 (22%) STT 3
Medial longitudinal fasciculus 4 (8%) 17 (34%) 9 (18%) MLF 4
Transverse fibers of the pons   33 (66%)   TFP 5
Spino cerebellar tract 6 (12%)    SCT 6
Central tegmental tract 3 (6%) 9 (18%) 8 (16%) CTT 7
Fronto pontine fibers    2 (4%) FPF 8
Parieto- occipito- temporo pontine fibers    3 (6%) POTPF 9
Lateral lemniscus   18 (36%) 6 (12%) LL 10
Inferior cerebellar peduncle 4 (8%)    ICP 11
Middle cerebellar peduncle   14 (28%)   MCP 12
Superior cerebellar peduncle   39 (78%) 3 (6%) SCP 13
Hypoglossal nucleus and nerve 14 (28%)    XII 14
Solitary nucleus and tract 20 (40%)    ST 15
Vague nerve 1 (2%)    X 15.1
Vestibular and cochlear nuclei and nerves 16 (32%) 17 (34%)   VIII 16
Facial nucleus and nerve   20 (40%)   VII 17
Abducens nucleus and nerve   17 (34%)   VI 18
Trigeminal tract 12 (24%) 15 (30%) 3 (6%) V 19
Oculomotor nucleus and nerve    7 (14%) III 20
Olivary complex 16 (32%)    OC 21
Red nucleus    3 (6%) RN 22
Substantia nigra    6 (12%) SN 23
Inferior colliculus    1 (2%) IC 24
Superior colliculus    1 (2%) SC 25
Periventricular gray 5 (10%) 20 (40%) 1 (2%) PVG 26
Periaqueductal gray    14 (28%) PAG 27
Raphe nuclei   13 (26%) 7 (14%) R 28
Reticular formation 2 (4%) 6 (12%) 4 (8%) RF