|
First author [reference]
|
Country
|
Inclusion period [in 2020]
|
No. of patient
|
RT-PCR positivity (%)
|
CO-RADS 5
|
≥ CO-RADS 4
|
≥ CO-RADS 3
|
|---|
|
Sen
|
Spe
|
PPV
|
NPV
|
Sen (%)
|
Spe (%)
|
PPV (%)
|
NPV (%)
|
Sen
|
Spe
|
PPV
|
NPV
|
|---|
|
de Jaegere [68]
|
Netherlands
|
3/12–3/23
|
96
|
47
|
62%
|
98%
|
96%
|
75%
|
84
|
92
|
91
|
87
|
–
|
–
|
–
|
–
|
|
Hermans [69]
|
Netherlands
|
3/27–4/20
|
319
|
42
|
75%
|
94%
|
90%
|
84%
|
90
|
88
|
85
|
93
|
93%
|
66%
|
66%
|
93%
|
|
De Smet [70]
|
Belgium
|
3/19–4/20
|
859
|
42
|
78%
|
93%
|
89%
|
86%
|
85
|
85
|
80
|
89
|
89%
|
85%
|
69%
|
90%
|
|
Fujioka [71]
|
Japan
|
Jan-Jun
|
154
|
49
|
53%
|
94%
|
90%
|
67%
|
68
|
88
|
85
|
74
|
–
|
–
|
–
|
–
|
|
Korevaar [72]
|
Netherlands
|
3/16–4/16
|
239
|
47
|
–
|
–
|
—
|
–
|
93
|
70
|
73
|
92
|
97%
|
51%
|
64%
|
96%
|
|
Bellini [73]
|
Italy
|
3/9–5/3
|
572
|
23
|
–
|
–
|
–
|
–
|
61
|
81
|
50
|
87
|
–
|
–
|
–
|
–
|
|
Tucato [74]
|
Italy
|
Unspecified
|
120
|
43
|
91%
|
91%
|
92%
|
90%
|
75
|
75
|
77
|
72
|
74%
|
76%
|
77%
|
72%
|
|
Nivet [75]
|
France
|
3/13–4/14
|
513
|
48
|
79%
|
97%
|
96%
|
84%
|
92
|
84
|
84
|
92
|
96%
|
43%
|
60%
|
92%
|
|
Inui [49]
|
Japan
|
1/30–6/30
|
100
|
50
|
65%
|
89%
|
86%
|
72%
|
86
|
68
|
73
|
83
|
91%
|
54%
|
66%
|
86%
|
|
Lieveld [76]
|
Neherlands
|
3/19–3/28
|
741
|
50
|
–
|
–
|
–
|
–
|
89
|
87
|
76
|
95
|
95%
|
54%
|
49%
|
96%
|
|
Schalekamp [77]
|
Netherlands
|
3/20–4/3
|
1070
|
50
|
71%
|
88%
|
86%
|
75%
|
86
|
81
|
82
|
85
|
92%
|
66%
|
73%
|
89%
|
|
Gross [78]
|
Germany
|
3/22–4/7
|
96
|
20
|
80%
|
99%
|
95%
|
95%
|
90
|
91
|
71
|
97
|
90%
|
63%
|
38%
|
96%
|
- CO-RADS the COVID-19 reporting and data system, RT-PCR real-time reverse transcription polymerase chain reaction; Sen, sensitivity, Spe specificity, PPV positive predictive value, NPV negative predictive value
