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Table 6 The results of ROC analysis including AUC, cut-off, sensitivity, and specific

From: Noninvasive assessment of kidney dysfunction in children by using blood oxygenation level-dependent MRI and intravoxel incoherent motion diffusion-weighted imaging

  

Healthy volunteers & CKD stage 1–3

CKD stage 1–3 & CKD stage 4–5

AUC (95% CI)

Cut-off

Sensitivity (%)

Specificity (%)

AUC (95% CI)

Cut-off

Sensitivity (%)

Specificity (%)

Cortex

T2*

0.752 (0.626–0.853)

49.5

47.06

100

0.931 (0.838–0.980)

46.78

82.35

100

ADC

0.766 (0.641–0.864)

1.892

56.86

90.91

0.928 (0.834–0.978)

1.78

88.2

91.7

Dt

0.851 (0.738–0.929)

1.697

60.78

100

0.823 (0.706–0.907)

1.616

80.39

83.33

Dp

0.761 (0.636–0.860)

19.33

74.51

100

0.553 (0.422–0.679)

12.75

43.14

91.67

fp

0.638 (0.506–0.756)

0.213

49.02

100

0.707 (0.578–0.815)

0.217

50.98

100

Medulla

T2*

0.735 (0.608–0.839)

25.6

62.75

81.82

0.935 (0.843–0.981)

22.9

92.16

83.33

ADC

0.736 (0.609–0.840)

1.830

76.47

72.73

0.882 (0.775–0.949)

1.629

82.35

83.33

Dt

0.832 (0.716–0.915)

1.611

76.47

90.91

0.770 (0.647–0.867)

1.509

82.35

66.67

Dp

0.734 (0.607–0.839)

17.96

68.63

100

0.529 (0.399–0.656)

15.29

37.25

91.67

fp

0.679 (0.548–0.792)

0.193

60.78

100

0.646 (0.516–0.763)

0.192

41.18

100

  1. The unit of T2* is ms; ADC, Dt and Dp value are given as × 10–3mm2/s. The f value is dimensionless
  2. ROC receiver operating characteristic, AUC area under the receiver operating characteristic curve, CI confidence interval, ADC apparent diffusion coefficient, Dt pure diffusion coefficient, Dp perfusion-related diffusion coefficient, fp pseudodiffusion fraction