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Table 6 The results of ROC analysis including AUC, cut-off, sensitivity, and specific

From: Noninvasive assessment of kidney dysfunction in children by using blood oxygenation level-dependent MRI and intravoxel incoherent motion diffusion-weighted imaging

   Healthy volunteers & CKD stage 1–3 CKD stage 1–3 & CKD stage 4–5
AUC (95% CI) Cut-off Sensitivity (%) Specificity (%) AUC (95% CI) Cut-off Sensitivity (%) Specificity (%)
Cortex T2* 0.752 (0.626–0.853) 49.5 47.06 100 0.931 (0.838–0.980) 46.78 82.35 100
ADC 0.766 (0.641–0.864) 1.892 56.86 90.91 0.928 (0.834–0.978) 1.78 88.2 91.7
Dt 0.851 (0.738–0.929) 1.697 60.78 100 0.823 (0.706–0.907) 1.616 80.39 83.33
Dp 0.761 (0.636–0.860) 19.33 74.51 100 0.553 (0.422–0.679) 12.75 43.14 91.67
fp 0.638 (0.506–0.756) 0.213 49.02 100 0.707 (0.578–0.815) 0.217 50.98 100
Medulla T2* 0.735 (0.608–0.839) 25.6 62.75 81.82 0.935 (0.843–0.981) 22.9 92.16 83.33
ADC 0.736 (0.609–0.840) 1.830 76.47 72.73 0.882 (0.775–0.949) 1.629 82.35 83.33
Dt 0.832 (0.716–0.915) 1.611 76.47 90.91 0.770 (0.647–0.867) 1.509 82.35 66.67
Dp 0.734 (0.607–0.839) 17.96 68.63 100 0.529 (0.399–0.656) 15.29 37.25 91.67
fp 0.679 (0.548–0.792) 0.193 60.78 100 0.646 (0.516–0.763) 0.192 41.18 100
  1. The unit of T2* is ms; ADC, Dt and Dp value are given as × 10–3mm2/s. The f value is dimensionless
  2. ROC receiver operating characteristic, AUC area under the receiver operating characteristic curve, CI confidence interval, ADC apparent diffusion coefficient, Dt pure diffusion coefficient, Dp perfusion-related diffusion coefficient, fp pseudodiffusion fraction