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Table 2 Baseline characteristics

From: Noninvasive assessment of kidney dysfunction in children by using blood oxygenation level-dependent MRI and intravoxel incoherent motion diffusion-weighted imaging

Characteristics

Healthy volunteers

CKD stage 1–3

CKD stage 4–5

p value

Sex

   

0.449

 Male

8

27

6

 

 Female

3

24

6

 

Age (years)

7.46 ± 2.58

9.84 ± 2.99

8.58 ± 3.80

0.051

eGFR (mL/min/1.73m2)

143.64 ± 24.02

105.67 ± 40.24

15.09 ± 9.16

 < 0.001

Serum creatinine (μmol/L)

34.58 ± 8.54

60.40 ± 34.66

462.09 ± 134.59

 < 0.001

ACR

13.75 ± 12.64

1644.82 ± 4244.70

5664.08 ± 10,473.95

 < 0.001

Serum albumin

45.48 ± 3.52

37.50 ± 9.09

36.84 ± 9.81

0.014

Cystatin C

0.83 ± 0.134

1.25 ± 0.64

4.73 ± 1.75

 < 0.001

Underlying disease

Henoch–Schonlein purpura nephritis

N/A

15

0

N/A

Lupus nephritis

N/A

3

1

N/A

IgA nephropathy

12

0

N/A

Nephrotic syndrome

N/A

17

5

N/A

Vesicoureteral reflux

N/A

1

1

N/A

Unknow

N/A

3

5

N/A

  1. Data are expressed as a number (gender and underlying disease) or means ± standard deviations
  2. eGFR estimated glomerular filtration rate, ACR albumin/creatinine ratio, N/A not applicable