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Table 4 Univariate and stepwise multivariate Cox proportional hazard regression analysis for prediction of short time outcome in CD

From: Computed tomography-based multiple body composition parameters predict outcomes in Crohn’s disease

Variable Univariate analysis Multivariate analysis
HR, 95% CI p value HR, 95% CI p value
Age 1.021 (0.997, 1.045) 0.095 1.040 (1.010, 1.070) 0.008
Sex (female) 0.783 (0.380, 1.613) 0.506 0.575 (0.246, 1.346) 0.202
Visceral/subcutaneous fat ratio 1.012 (1.002, 1.021) 0.016 1.001 (0.991, 1.012) 0.818
Skeletal muscle principal component 0.852 (0.725, 1.001) 0.051
Adipose tissue principal component 0.873 (0.769, 0.991) 0.035 0.872 (0.772, 0.986) 0.029
Perianal disease (yes) 1.595 (0.885, 2.873) 0.120 1.841 (0.989, 3.427) 0.054
Smoking status (yes) 1.151 (0.517, 2.563) 0.731 0.625 (0.268, 1.456) 0.276
Disease behavior (complicated) 2.865 (1.600, 5.131) < 0.001 3.244 (1.749, 6.012) < 0.001
  1. CD Crohn’s disease, HR hazard ratio, CI confidence interval; visceral/subcutaneous fat ratio, area of visceral fat/area of subcutaneous fat, p values lower than 0.05 are presented in bold