From: Computed tomography-based multiple body composition parameters predict outcomes in Crohn’s disease
All | Complicated | Inflammatory | p value | |
---|---|---|---|---|
Demographic data | n = 122 | n = 54 | n = 68 | |
Age (years) | 32.5 ± 12.04 | 33.85 ± 12.70 | 30.79 ± 11.41 | 0.165 |
Sex | 0.181 | |||
Male | 95 | 39 | 56 | |
Female | 27 | 15 | 12 | |
Current smoker | 0.062 | |||
Yes | 15 | 10 | 5 | |
No | 107 | 44 | 63 | |
Locationa | 0.263 | |||
L1 | 49 | 26 | 23 | |
L2 | 27 | 11 | 16 | |
L3 | 46 | 17 | 29 | |
Perianal disease | 0.630 | |||
Yes | 32 | 13 | 19 | |
No | 90 | 41 | 49 | |
Duration of disease (years) | 2.19 ± 2.93 | 2.33 ± 2.90 | 2.08 ± 2.97 | 0.653 |
C-reactive protein (mg/L)b | 43.03 ± 41.41 (n = 107) | 47.02 ± 48.08 (n = 44) | 40.25 ± 36.19 (n = 63) | 0.408 |
Serum albumin (g/L)b | 35.13 ± 6.67 (n = 120) | 34.66 ± 6.78 (n = 54) | 35.52 ± 6.57 (n = 66) | 0.481 |
Erythrocyte sedimentation rate (mm/h)b | 26.59 ± 22.75 (n = 111) | 27.67 ± 23.82 (n = 46) | 25.82 ± 22.12 (n = 65) | 0.674 |
BMI (kg/m2) | 18.49 ± 2.80 | 17.88 ± 2.66 | 19.19 ± 2.82 | 0.034 |
Sacorpenia | 0.604 | |||
Yes | 84 | 39 | 45 | |
No | 38 | 15 | 23 | |
Baseline medications | ||||
Diagnostic anti-tuberculosis therapy | 30 | 8 | 22 | 0.025 |
Nutritional supplement | 106 | 51 | 55 | 0.028 |
Anti-TNF | 20 | 11 | 9 | 0.290 |
Corticosteroids | 30 | 9 | 21 | 0.070 |
Immunomodulator | 16 | 5 | 11 | 0.261 |
Mesalazine | 58 | 20 | 38 | 0.038 |
Follow-up outcomes | ||||
Adverse outcome | n = 49 | n = 31 | n = 18 | 0.775 |
Surgery | 32 | 20 | 12 | |
Start of anti-TNF therapy | 4 | 2 | 2 | |
Escalation of biologic therapy | 13 | 9 | 4 |